Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50004684
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022271BDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataIC50: 1.40E+3nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataKi:  4.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485550BDBM50485550(CHEBI:17859 | Glutarate)
Affinity DataIC50: 4.90E+3nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 6.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240008BDBM50240008(CHEBI:104011 | Aminohippuric Acid | PAHA | Para-Am...)
Affinity DataIC50: 8.80E+3nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001103BDBM50001103(9-[2-phosphonomethoxyethyl]adenine | 9-(2-(phospho...)
Affinity DataIC50: 2.80E+4nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31915BDBM31915(HPMPC | Vistide | CDV | Cidofovir | US10071110, Co...)
Affinity DataIC50: 6.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26193BDBM26193(salicylic acid | 2-Hydroxybenzoate, I | CHEMBL424 ...)
Affinity DataIC50: 2.80E+5nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485549BDBM50485549(Cyclic Cidofovir | Cyclic(S)-HPMPC)
Affinity DataIC50: 1.10E+6nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103624BDBM50103624(CHEBI:3537 | 40602 | Cefaloridine | Cephaloridine ...)
Affinity DataIC50: 1.25E+6nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370585BDBM50370585(Anspor | Cefradine | CEPHRADINE)
Affinity DataIC50: 1.60E+6nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed