Compile Data Set for Download or QSAR
Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 50010049
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090364BDBM50090364(3-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  0.800nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074025BDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataIC50: 1.30nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090350BDBM50090350(4-Ethyl-3-(4-methoxy-benzenesulfonyl)-octanoic aci...)
Affinity DataKi:  4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090355BDBM50090355(7-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-benzenesu...)
Affinity DataIC50: 6.40nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090352BDBM50090352(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-7-p...)
Affinity DataIC50: 6.90nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090372BDBM50090372(3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic a...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090347BDBM50090347(3-Cyclohexyl-N-hydroxy-3-(4-methoxy-benzenesulfony...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090373BDBM50090373(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-non...)
Affinity DataIC50: 9.5nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090371BDBM50090371(7-Benzo[1,3]dioxol-5-yl-3-(3-cyclopentyloxy-4-meth...)
Affinity DataIC50: 11nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090359BDBM50090359(3-(3,4-Dimethoxy-benzenesulfonyl)-6-phenyl-hexanoi...)
Affinity DataIC50: 14nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090383BDBM50090383(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-6-(...)
Affinity DataIC50: 16nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074027BDBM50074027(3-(4-Methoxy-benzenesulfonyl)-7-phenyl-heptanoic a...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090360BDBM50090360(3-(4-Benzyloxy-phenyl)-3-(3-cyclopentyloxy-4-metho...)
Affinity DataIC50: 21nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090377BDBM50090377(3-(4-Methoxy-benzenesulfonyl)-5,7,7-trimethyl-octa...)
Affinity DataKi:  27nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089209BDBM50089209(3-(4-Methoxy-benzenesulfonyl)-heptanoic acid hydro...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090376BDBM50090376(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-p...)
Affinity DataIC50: 31nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090366BDBM50090366(3-(4-Methoxy-benzenesulfonyl)-nonanoic acid hydrox...)
Affinity DataKi:  31nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090386BDBM50090386(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-6-(...)
Affinity DataIC50: 32nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090354BDBM50090354(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-(...)
Affinity DataIC50: 32nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090381BDBM50090381(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-7-(...)
Affinity DataIC50: 36nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090357BDBM50090357(5-Cyclohexyl-3-(4-methoxy-benzenesulfonyl)-pentano...)
Affinity DataKi:  36nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090382BDBM50090382(4-Benzyloxy-N-hydroxy-3-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  38nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074021BDBM50074021(3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...)
Affinity DataKi:  43nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074028BDBM50074028(3-(4-Methoxy-benzenesulfonyl)-6-phenyl-hexanoic ac...)
Affinity DataKi:  44nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090346BDBM50090346(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)
Affinity DataIC50: 49nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090356BDBM50090356(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-hex...)
Affinity DataIC50: 50nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090342BDBM50090342(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-hex...)
Affinity DataIC50: 55nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090364BDBM50090364(3-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  60nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090363BDBM50090363(5-(4-Benzyloxy-phenyl)-3-(3-cyclopentyloxy-4-metho...)
Affinity DataIC50: 63nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090378BDBM50090378(5-(4-Benzyloxy-phenyl)-3-(3,4-dimethoxy-benzenesul...)
Affinity DataIC50: 64nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090347BDBM50090347(3-Cyclohexyl-N-hydroxy-3-(4-methoxy-benzenesulfony...)
Affinity DataKi:  86nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090370BDBM50090370(4-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  88nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090361BDBM50090361(3-(3-Benzyloxy-phenyl)-3-(3-cyclopentyloxy-4-metho...)
Affinity DataIC50: 89nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090353BDBM50090353(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-m...)
Affinity DataIC50: 102nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090379BDBM50090379(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-hep...)
Affinity DataIC50: 118nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090345BDBM50090345(Methyl-phenyl-carbamic acid 3-(3-cyclopentyloxy-4-...)
Affinity DataIC50: 140nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090350BDBM50090350(4-Ethyl-3-(4-methoxy-benzenesulfonyl)-octanoic aci...)
Affinity DataKi:  184nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090369BDBM50090369(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)
Affinity DataIC50: 260nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090343BDBM50090343(N-Hydroxy-3-(4-methoxy-benzenesulfonyl)-3-phenyl-p...)
Affinity DataKi:  270nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090374BDBM50090374(N-Hydroxy-3-(4-methoxy-benzenesulfonyl)-3-(4-pheno...)
Affinity DataIC50: 280nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090348BDBM50090348(7-(3,4-Dihydro-2H-quinolin-1-yl)-3-(3,4-dimethoxy-...)
Affinity DataIC50: 295nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090372BDBM50090372(3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic a...)
Affinity DataKi:  300nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074021BDBM50074021(3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...)
Affinity DataKi:  350nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090350BDBM50090350(4-Ethyl-3-(4-methoxy-benzenesulfonyl)-octanoic aci...)
Affinity DataKi:  357nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090357BDBM50090357(5-Cyclohexyl-3-(4-methoxy-benzenesulfonyl)-pentano...)
Affinity DataKi:  400nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089209BDBM50089209(3-(4-Methoxy-benzenesulfonyl)-heptanoic acid hydro...)
Affinity DataKi:  404nMAssay Description:In vitro inhibition of human recombinant Matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090349BDBM50090349([3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-4-...)
Affinity DataIC50: 460nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090368BDBM50090368(3-(4-Benzyloxy-phenyl)-N-hydroxy-3-(4-methoxy-benz...)
Affinity DataIC50: 520nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090362BDBM50090362(6-(3,4-Dihydro-2H-quinolin-1-yl)-3-(3,4-dimethoxy-...)
Affinity DataIC50: 564nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090380BDBM50090380(3-(3,4-Dimethoxy-benzenesulfonyl)-N-hydroxy-3-phen...)
Affinity DataIC50: 580nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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