Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50036837
TargetProthrombin(Bos taurus (Bovine))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:Inhibitory Activity against bovine thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50091037(1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tet...)
Affinity DataKi:  19nMAssay Description:Inhibitory Activity against bovine alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...)
Affinity DataKi:  31nMAssay Description:Inhibitory Activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  150nMAssay Description:Inhibitory Activity against human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...)
Affinity DataKi:  300nMAssay Description:Inhibitory Activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  360nMAssay Description:Inhibitory Activity against bovine trypsinMore data for this Ligand-Target Pair
TargetTrypsin-3(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  690nMAssay Description:Inhibitory Activity against bovine beta-trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50091037(1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tet...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory Activity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibitory Activity against bovine Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50091037(1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tet...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibitory Activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50084676((2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PEN...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50:  70nMAssay Description:Inhibitory Activity against human Coagulation factor XMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50084676((2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PEN...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibitory Activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed