Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50035066
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091497((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18128((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091496((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18128((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed