Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50035070
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091723((S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091720((S)-3-[(1R,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091725((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091717((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091718((S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091726((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091721((S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091715((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366647(CHEMBL1789975)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091724((S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091714((S)-3-[(1S,3S)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091727((S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091716((S)-3-[(1S,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091722((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091719((S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091715((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091724((S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091713((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091719((S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091727((S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091715((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091719((S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091723((S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091724((S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  28nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091726((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091727((S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091718((S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  39nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091718((S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-y...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091721((S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  70nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091726((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  91nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091714((S)-3-[(1S,3S)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  95nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091721((S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  97nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091714((S)-3-[(1S,3S)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  120nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091713((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091723((S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091713((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  170nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091720((S)-3-[(1R,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091722((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  290nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091717((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  320nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091725((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  350nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091725((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  500nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091722((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  550nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366647(CHEMBL1789975)
Affinity DataKi:  620nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091716((S)-3-[(1S,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  660nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091720((S)-3-[(1R,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  660nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091716((S)-3-[(1S,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)...)
Affinity DataKi:  730nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091717((S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366647(CHEMBL1789975)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed