Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50010193
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091931BDBM50091931(1-[5-tert-Butyl-2-(3-nitro-phenyl)-2H-pyrazol-3-yl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091935BDBM50091935(1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13336BDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 20nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091954BDBM50091954(1-[2-(4-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 29nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091951BDBM50091951(1-(5-tert-Butyl-2-phenyl-2H-pyrazol-3-yl)-3-(2,3-d...)
Affinity DataIC50: 30nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091933BDBM50091933(1-[5-tert-Butyl-2-(4-methanesulfonyl-phenyl)-2H-py...)
Affinity DataIC50: 32nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091939BDBM50091939(1-[5-tert-Butyl-2-(3-fluoro-phenyl)-2H-pyrazol-3-y...)
Affinity DataIC50: 33nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091936BDBM50091936(1-[5-tert-Butyl-2-(3-methoxy-phenyl)-2H-pyrazol-3-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091952BDBM50091952(1-[5-tert-Butyl-2-(4-nitro-phenyl)-2H-pyrazol-3-yl...)
Affinity DataIC50: 39nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091932BDBM50091932(1-[5-tert-Butyl-2-(4-chloro-phenyl)-2H-pyrazol-3-y...)
Affinity DataIC50: 42nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091937BDBM50091937(1-(5-tert-Butyl-2-o-tolyl-2H-pyrazol-3-yl)-3-(2,3-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091943BDBM50091943(1-(5-tert-Butyl-2H-pyrazol-3-yl)-3-(2,3-dichloro-p...)
Affinity DataIC50: 44nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091935BDBM50091935(1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091923BDBM50091923(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-(2,3-d...)
Affinity DataIC50: 53nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091946BDBM50091946(1-[5-tert-Butyl-2-(4-methoxy-phenyl)-2H-pyrazol-3-...)
Affinity DataIC50: 53nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091938BDBM50091938(1-[5-tert-Butyl-2-(3-trifluoromethyl-phenyl)-2H-py...)
Affinity DataIC50: 56nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091945BDBM50091945(1-[5-tert-Butyl-2-(2,2,2-trifluoro-ethyl)-2H-pyraz...)
Affinity DataIC50: 87nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091941BDBM50091941({3-tert-Butyl-5-[3-(2,3-dichloro-phenyl)-ureido]-p...)
Affinity DataIC50: 105nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091940BDBM50091940(1-[5-tert-Butyl-2-(4-isopropyl-phenyl)-2H-pyrazol-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091950BDBM50091950(1-(5-tert-Butyl-2-pyridin-2-yl-2H-pyrazol-3-yl)-3-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091942BDBM50091942(1-(5-tert-Butyl-2-phenyl-thiophen-3-yl)-3-(2,3-dic...)
Affinity DataIC50: 130nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091947BDBM50091947(1-[5-tert-Butyl-2-(2-hydroxy-ethyl)-2H-pyrazol-3-y...)
Affinity DataIC50: 130nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091948BDBM50091948(1-[5-tert-Butyl-2-(2-cyano-ethyl)-2H-pyrazol-3-yl]...)
Affinity DataIC50: 180nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091949BDBM50091949(2-{3-tert-Butyl-5-[3-(2,3-dichloro-phenyl)-ureido]...)
Affinity DataIC50: 250nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091953BDBM50091953(4-[3-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-ureid...)
Affinity DataIC50: 290nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091934BDBM50091934(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-(3,5-d...)
Affinity DataIC50: 325nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091930BDBM50091930(N-(3-{3-tert-Butyl-5-[3-(2,3-dichloro-phenyl)-urei...)
Affinity DataIC50: 500nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091944BDBM50091944(1-Biphenyl-3-yl-3-(5-tert-butyl-2-methyl-2H-pyrazo...)
Affinity DataIC50: 797nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091935BDBM50091935(1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 850nMAssay Description:Inhibition of c-Jun N-terminal kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091935BDBM50091935(1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed