Compile Data Set for Download or QSAR
Report error Found 83 Enz. Inhib. hit(s) with all data for entry = 50036846
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078437BDBM50078437((S)-3-{[5-(2-Piperidin-4-yl-ethyl)-thieno[2,3-b]th...)
Affinity DataKd:  0.0700nMAssay Description:Dissociation constant for alpha IIb beta-3 integrin rested plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369582BDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataKi:  0.100nMAssay Description:Dissociation constant for [3H]-DMP728 binding to alphaIIb beta III integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078433BDBM50078433(2-Benzenesulfonylamino-3-{[5-(2-piperidin-4-yl-eth...)
Affinity DataKd:  0.150nMAssay Description:Dissociation constant for alpha IIb beta-3 integrin rested plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058236BDBM50058236((S)-2-(Butane-1-sulfonylamino)-3-{[4-oxo-5-(2-pipe...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant for alpha IIb beta-3 integrin rested plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054825BDBM50054825([(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataKd:  1.90nMAssay Description:Inhibition of alpha IIb beta III mediated platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078442BDBM50078442(3-{[3-Oxo-2-(2-piperidin-4-yl-ethyl)-2,3-dihydro-1...)
Affinity DataKd:  2.20nMAssay Description:Dissociation constant for alpha IIb beta-3 integrin rested plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369582BDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092095BDBM50092095([16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [125]fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092115BDBM50092115(2-Benzenesulfonylamino-3-{[2-(4-piperidin-4-yl-pip...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human platelet aggregation in platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033030BDBM50033030(3-{2-[2-Oxo-3-(2-piperidin-4-yl-ethyl)-piperidin-1...)
Affinity DataKd:  4.5nMAssay Description:Dissociation constant for alpha IIb beta-3 integrin activated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078433BDBM50078433(2-Benzenesulfonylamino-3-{[5-(2-piperidin-4-yl-eth...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092117BDBM50092117((S)-2-Benzenesulfonylamino-3-{[4-oxo-5-(2-piperidi...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078437BDBM50078437((S)-3-{[5-(2-Piperidin-4-yl-ethyl)-thieno[2,3-b]th...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092103BDBM50092103(Gantofiban | (4-{(R)-3-[4-(Imino-methoxycarbonylam...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058236BDBM50058236((S)-2-(Butane-1-sulfonylamino)-3-{[4-oxo-5-(2-pipe...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092120BDBM50092120((S)-3-{[2-(4-Carbamimidoyl-phenyl)-benzooxazole-5-...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054538BDBM50054538(L-767679 | 3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydr...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092097BDBM50092097(2-Benzenesulfonylamino-3-{[5-(piperidin-4-ylmethox...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078442BDBM50078442(3-{[3-Oxo-2-(2-piperidin-4-yl-ethyl)-2,3-dihydro-1...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092101BDBM50092101(7-(4-Carbamimidoyl-benzoylamino)-3-(3-methyl-butyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076058BDBM50076058(2-((S)-Benzenesulfonylamino)-3-(4-piperazin-1-yl-b...)
Affinity DataIC50: 17nMAssay Description:Inhibition of platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092125BDBM50092125({4-[4-(4-Carbamimidoyl-phenyl)-piperazin-1-yl]-phe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of glycoprotein IIb/III and platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092121BDBM50092121(3-{2-[4-(4-Carbamimidoyl-phenyl)-4-methyl-2,5-diox...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human gel filtered platelet aggregation induced by ADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092105BDBM50092105(2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-5-oxo-5...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092128BDBM50092128(3-[(2-{4-[(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-imi...)
Affinity DataIC50: 22nMAssay Description:Inhibition of platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033030BDBM50033030(3-{2-[2-Oxo-3-(2-piperidin-4-yl-ethyl)-piperidin-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of alpha IIb beta-3 integrin mediated platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078448BDBM50078448(3-{[3-Oxo-2-(2-piperidin-4-yl-ethyl)-2,3-dihydro-1...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092127BDBM50092127(8-Acetylamino-22-(4-aminomethyl-benzyl)-5-carbamoy...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human gel filtered platelet aggregation mediated by 10 uM ADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092100BDBM50092100(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{2-[ethyl-(4-pipe...)
Affinity DataIC50: 28nMAssay Description:Inhibition of fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054825BDBM50054825([(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataIC50: 28nMAssay Description:inhibition of ADP-induced platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075566BDBM50075566(CHEMBL117989 | CHEMBL275611 | (S)-3-{2-[(R)-3-(4-C...)
Affinity DataIC50: 29nMAssay Description:Inhibition of unactivated human platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092110BDBM50092110(2-[13-[3-amino(imino)methylaminopropyl]-14-methyl-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092124BDBM50092124(2-{2-[3-(4-Carbamimidoyl-benzoylamino)-propionylam...)
Affinity DataIC50: 30nMAssay Description:Inhibition of platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003874BDBM50003874(CHEMBL108111 | {1-[2-(4-Carbamimidoyl-benzoylamino...)
Affinity DataIC50: 30nMAssay Description:Inhibition of platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067217BDBM50067217({(S)-6-[4-(Imino-morpholin-4-yl-methyl)-benzoylami...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061849BDBM50061849(2-Benzenesulfonylamino-3-{3-[(5-carbamimidoyl-benz...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004058BDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 36nMAssay Description:Inhibition of platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069438BDBM50069438(2-(Butane-1-sulfonylamino)-5-[2,4-dioxo-3-(2-piper...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062783BDBM50062783({1-[2-(4-Carbamimidoyl-benzoylamino)-acetyl]-4-car...)
Affinity DataIC50: 38nMAssay Description:Inhibition of alpha IIb beta-3 integrin mediated platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092123BDBM50092123(((S)-1-{2-[4-(N-Hydroxycarbamimidoyl)-benzoylamino...)
Affinity DataIC50: 38nMAssay Description:inhibition of platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003867BDBM50003867({1-[2-(4-Carbamimidoyl-benzoylamino)-propionyl]-pi...)
Affinity DataIC50: 38nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069435BDBM50069435(2-(Butane-1-sulfonylamino)-5-[2-methyl-4-oxo-3-(2-...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092126BDBM50092126(2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-[(3-p...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092119BDBM50092119((1-{3-[2-Fluoro-4-(imino-thiazolidin-3-yl-methyl)-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of alpha IIb beta-3 integrin mediated platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369582BDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataIC50: 46nMAssay Description:Inhibition of human platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092106BDBM50092106(2-Butoxycarbonylamino-3-{[3-(4-carbamimidoyl-benzy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092099BDBM50092099(3-Methyl-4-[4-(4-pyridin-4-yl-piperazin-1-yl)-phen...)
Affinity DataIC50: 50nMAssay Description:Inhibition of glycoprotein IIb/III and platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092116BDBM50092116(3-[8-(4-Carbamimidoyl-benzoylamino)-6-oxo-4H,6H-1,...)
Affinity DataIC50: 54nMAssay Description:Inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092113BDBM50092113(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50: 59nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50037970BDBM50037970({4-[4-(4-Carbamimidoyl-phenyl)-piperazin-1-yl]-pip...)
Affinity DataIC50: 59nMAssay Description:Inhibition of glycoprotein IIb/III and platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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