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Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50010269
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092632(8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092630(8-(3-Azido-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092626(8-(3-Azido-phenyl)-6-(4-iodo-imidazol-1-ylmethyl)-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092623(3-Benzyl-5-phenyl-3,5-dihydro-1,3,5,6-tetraaza-cyc...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092633(8-(3-Azido-phenyl)-6-iodo-quinoline | CHEMBL127994)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092627(8-(5-Azido-2-iodo-phenyl)-6-pyridin-4-ylmethyl-qui...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092624(6-Imidazol-1-ylmethyl-8-phenyl-quinoline | CHEMBL4...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092629(CHEMBL123576 | [8-(3-Iodo-phenyl)-quinolin-6-yl]-p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092628(6-Azido-8-(3-iodo-phenyl)-quinoline | CHEMBL124575)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092631(4-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-[3-iodo-5-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092625(3-[3-Iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)-b...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed