Compile Data Set for Download or QSAR
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Found 41 Enz. Inhib. hit(s) with all data for entry = 50036870
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM27213(4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...)
Affinity DataKi:  0.490nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.600nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092853(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-propan...)
Affinity DataKi:  0.740nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50091386(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...)
Affinity DataKi:  0.800nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092841(CHEMBL128690 | Cyclobutyl-{4-[3-(1H-imidazol-4-yl)...)
Affinity DataKi:  0.890nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092846(1-{2-Fluoro-4-[3-(1H-imidazol-4-yl)-propoxy]-pheny...)
Affinity DataKi:  1.10nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092848(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-methyl-pheny...)
Affinity DataKi:  1.20nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092845(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-butan-...)
Affinity DataKi:  1.90nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092844(4-[3-(4-Methoxy-phenoxy)-propyl]-1H-imidazole; com...)
Affinity DataKi:  2.20nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50067472(4-[3-(4-Ethynyl-phenoxy)-propyl]-1H-imidazole | 4-...)
Affinity DataKi:  2.30nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092843(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-hexan-...)
Affinity DataKi:  2.5nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092838(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-pentan...)
Affinity DataKi:  2.60nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  4nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092850(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-2-meth...)
Affinity DataKi:  4.80nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092856(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-3-methyl-pheny...)
Affinity DataKi:  4.80nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092834(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-2-phen...)
Affinity DataKi:  5.90nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092865(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-heptan...)
Affinity DataKi:  7nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092855(CHEMBL129146 | Cyclopentyl-{4-[3-(1H-imidazol-4-yl...)
Affinity DataKi:  7.20nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092863(CHEMBL128495 | {4-[3-(1H-Imidazol-4-yl)-propoxy]-p...)
Affinity DataKi:  8.90nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50053278(4-[3-(1H-Imidazol-4-yl)-propoxy]-benzonitrile | 4-...)
Affinity DataKi:  12nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092836(4-[3-(1H-Imidazol-4-yl)-propoxy]-benzaldehyde; com...)
Affinity DataKi:  12nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092857(6-[3-(1H-Imidazol-4-yl)-propoxy]-3,4-dihydro-2H-na...)
Affinity DataKi:  13nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092849(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-trifluoromet...)
Affinity DataKi:  17nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092862(5-[3-(1H-Imidazol-4-yl)-propoxy]-indan-1-one; comp...)
Affinity DataKi:  17nMAssay Description:Compounds were tested for their effect at histamine H3 receptors in vitro on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092852(4-[3-(1H-Imidazol-4-yl)-propoxy]-phenol; compound ...)
Affinity DataKi:  18nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092854(4-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-but-3-...)
Affinity DataKi:  20nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092835(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-3,3-di...)
Affinity DataKi:  27nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092847(3-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-propen...)
Affinity DataKi:  32nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092837(4-[3-(Indan-5-yloxy)-propyl]-1H-imidazole with (0....)
Affinity DataKi:  38nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092858(4-[3-(4-Methanesulfonyl-phenoxy)-propyl]-1H-imidaz...)
Affinity DataKi:  40nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092864(4-[3-(5,6,7,8-Tetrahydro-naphthalen-2-yloxy)-propy...)
Affinity DataKi:  45nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092859(5-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-5-oxo-...)
Affinity DataKi:  49nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092860(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-propan...)
Affinity DataKi:  53nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092833(4-(3-Phenoxy-propyl)-1H-imidazole with (0.95M)oxal...)
Affinity DataKi:  55nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092840(1-{2-Fluoro-4-[3-(1H-imidazol-4-yl)-propoxy]-pheny...)
Affinity DataKi:  57nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092839(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2,6-dimethyl-p...)
Affinity DataKi:  90nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092866(4-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-butan-...)
Affinity DataKi:  91nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092851(5-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-5-oxo-...)
Affinity DataKi:  122nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092861(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-methoxy-phen...)
Affinity DataKi:  325nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50092867(4-(8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-...)
Affinity DataKi:  410nMAssay Description:Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM27213(4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition against histamine-metabolizing enzyme Histamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed