Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with all data for entry = 50035087
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093208(2-(5-Bromo-1H-indol-3-yl)-N-[3-(4-{3-[2-(5-bromo-1...)
Affinity DataKi:  76nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50240622(3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydr...)
Affinity DataKi:  76nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093209(2-(5-Methoxy-1H-indol-3-yl)-N-[3-(4-{3-[2-(5-metho...)
Affinity DataKi:  280nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093210(3-(1H-Indol-3-yl)-N-(3-{4-[3-(2-1H-indol-3-yl-acet...)
Affinity DataKi:  350nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093205(2-(1H-Indol-3-yl)-N-(3-{4-[3-(2-1H-indol-3-yl-acet...)
Affinity DataKi:  390nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093206(CHEMBL78036 | Spermine derivative)
Affinity DataKi:  750nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093211(CHEMBL308396 | Spermine derivative)
Affinity DataKi:  850nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093204(4-(1H-Indol-3-yl)-N-(3-{4-[3-(4-1H-indol-3-yl-buty...)
Affinity DataKi:  1.26E+3nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093207((E)-3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[(E)-3-(3,...)
Affinity DataKi:  1.39E+3nMAssay Description:The compound was evaluated for inhibition of trypanothione reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Southamton

Curated by ChEMBL
LigandPNGBDBM50093207((E)-3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[(E)-3-(3,...)
Affinity DataKi: >1.00E+7nMAssay Description:The compound was evaluated for inhibition of human Glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed