Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50010608
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096730(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096729((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Benzylaminooxaly...)
Affinity DataIC50:  4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096726(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50:  4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096734((S)-4-[(S)-3-Carboxy-2-(3-carboxy-propionylamino)-...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096727((S)-4-[(S)-3-Carboxy-2-(3-carboxy-propionylamino)-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096725(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against delta receptor of (endomorphin 2) in mouse vas deferens was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096733(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50:  7nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096728((S)-4-((S)-1-{(S)-1-[(S)-1-((S)-1-Amino-2-carbamoy...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096732(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096724((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Aminooxalyl-pent...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096724((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Aminooxalyl-pent...)
Affinity DataIC50:  300nMAssay Description:Compound was tested for inhibition of Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096731(4-[3-Carboxy-2-(3-carboxy-propionylamino)-propiony...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096724((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Aminooxalyl-pent...)
Affinity DataIC50:  1.20E+4nMAssay Description:Compound was tested for inhibition of ElastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Roche Discover Welwyn

Curated by ChEMBL
LigandPNGBDBM50096724((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Aminooxalyl-pent...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against Opioid receptor mu 1 of (endomorphin 2) in guinea pig ileum was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed