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Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50035195
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  47nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097572(6-Chloro-4-(1-hydroxy-cyclopropylethynyl)-4-triflu...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097571((S)-6-Chloro-4-cyclopropylethynyl-8-hydroxy-4-trif...)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097575(6-Chloro-4-cyclopropylethynyl-7-hydroxy-4-trifluor...)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097573((2S,3S,4S,5R,6S)-6-((S)-6-Chloro-4-cyclopropylethy...)
Affinity DataIC50:  9.49E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097576((S)-6-Chloro-4-cyclopropylethynyl-8-hydroxy-4-trif...)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097574(CHEMBL346585 | Sulfuric acid mono-((S)-6-chloro-4-...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed