Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50010824
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 21nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099120(5-(2-Hydroxy-ethyl)-5-(4-phenoxy-phenyl)-pyrimidin...)
Affinity DataIC50: 59nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: 65nMAssay Description:Inhibition of collagenase-3, Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 78nMAssay Description:Inhibition of collagenase-3, Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: 81nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099120(5-(2-Hydroxy-ethyl)-5-(4-phenoxy-phenyl)-pyrimidin...)
Affinity DataIC50: 118nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50: 164nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50: 330nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50: 530nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 696nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 863nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 868nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 898nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50: 930nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099124(1,5-Dimethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099122(5-Biphenyl-4-yl-5-hexyl-2-thioxo-dihydro-pyrimidin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099120(5-(2-Hydroxy-ethyl)-5-(4-phenoxy-phenyl)-pyrimidin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099122(5-Biphenyl-4-yl-5-hexyl-2-thioxo-dihydro-pyrimidin...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099122(5-Biphenyl-4-yl-5-hexyl-2-thioxo-dihydro-pyrimidin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099124(1,5-Dimethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099124(1,5-Dimethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099124(1,5-Dimethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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