Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50036932
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22541(VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...)
Affinity DataKd:  0.158nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099623(4-[2-(4,4-Dimethyl-pent-1-ynyl)-cyclopropyl]-1H-im...)
Affinity DataKi:  0.180nMAssay Description:Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099622(1-Cyclohexylmethyl-3-[2-(1H-imidazol-4-yl)-cyclopr...)
Affinity DataKi:  0.400nMAssay Description:Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85830(VUF5202)
Affinity DataKd:  1.26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKd:  1.26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKd:  3.98nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22916(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Affinity DataKd:  5.01nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409211(CHEMBL45027)
Affinity DataKd:  6.17nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071496(N-(4-Chloro-benzyl)-2-[4-(1H-imidazol-4-ylmethyl)-...)
Affinity DataKi:  7nMAssay Description:Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409217(CHEMBL45056)
Affinity DataKd:  7.94nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407372(CHEMBL44220)
Affinity DataKd:  10nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50050183((4-Iodo-benzyl)-carbamic acid 3-(1H-imidazol-4-yl)...)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099624((4-Chloro-phenyl)-acetic acid 3-(1H-imidazol-4-yl)...)
Affinity DataKi:  14nMAssay Description:Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKd:  25.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409218(CHEMBL45342)
Affinity DataKd:  50.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409200(CHEMBL412882)
Affinity DataKd:  61.7nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed