Compile Data Set for Download or QSAR
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Found 55 Enz. Inhib. hit(s) with all data for entry = 50035126
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099875((E)-2-Amino-5-(2,4-difluoro-phenyl)-5-(4-isopropyl...)
Affinity DataIC50:  150nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099886((E)-2-Amino-5-(3,4-diethyl-phenyl)-5-(2,4-difluoro...)
Affinity DataIC50:  283nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099859(CHEMBL29220 | Sodium; (E)-2-amino-5-(2-fluoro-phen...)
Affinity DataIC50:  290nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099862(CHEMBL28746 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  330nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099878((E)-2-Amino-5-(2,4-difluoro-phenyl)-5-naphthalen-2...)
Affinity DataIC50:  365nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099882(CHEMBL29958 | Sodium; (Z)-2-amino-5-(4-isopropyl-p...)
Affinity DataIC50:  400nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099879(CHEMBL28601 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  460nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099866(CHEMBL418388 | Sodium; (E)-2-amino-5-(3,4-diethyl-...)
Affinity DataIC50:  660nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099883(CHEMBL28577 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  770nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099858(CHEMBL285370 | Sodium; (E)-2-amino-5-(4-isopropyl-...)
Affinity DataIC50:  1.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099873(CHEMBL29964 | Sodium; (E)-2-amino-5-(4-isopropyl-p...)
Affinity DataIC50:  1.16E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099863(CHEMBL29023 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  1.17E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099868(CHEMBL27914 | Sodium; (E)-2-amino-5-biphenyl-3-yl-...)
Affinity DataIC50:  1.34E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099861(CHEMBL28549 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  1.59E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099881((E)-2-Amino-5-(4-tert-butyl-phenyl)-5-(2,4-difluor...)
Affinity DataIC50:  1.74E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099865(CHEMBL283017 | Sodium; 2-amino-5,5-bis-(4-isopropy...)
Affinity DataIC50:  2.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099880(CHEMBL29279 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  2.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099885(CHEMBL281450 | Sodium; (E)-2-amino-5-biphenyl-4-yl...)
Affinity DataIC50:  2.06E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099864(CHEMBL27850 | Sodium; (Z)-2-amino-5-biphenyl-4-yl-...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099872(CHEMBL285592 | Sodium; (E)-2-amino-5-(4-cyano-phen...)
Affinity DataIC50:  2.64E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099870(CHEMBL29022 | Sodium; (E)-2-amino-5-biphenyl-2-yl-...)
Affinity DataIC50:  2.75E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099864(CHEMBL27850 | Sodium; (Z)-2-amino-5-biphenyl-4-yl-...)
Affinity DataIC50:  3.40E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099877(CHEMBL29396 | Sodium; (E)-2-amino-5-biphenyl-4-yl-...)
Affinity DataIC50:  3.66E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099871(CHEMBL286706 | Sodium; (E)-2-amino-5-(4-tert-butyl...)
Affinity DataIC50:  5.47E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099858(CHEMBL285370 | Sodium; (E)-2-amino-5-(4-isopropyl-...)
Affinity DataIC50:  5.77E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099874(CHEMBL28016 | Sodium; (Z)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  5.88E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099867(CHEMBL28570 | Sodium; (E)-2-amino-5-(4-isopropyl-p...)
Affinity DataIC50:  5.93E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099884(CHEMBL29256 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  6.44E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099867(CHEMBL28570 | Sodium; (E)-2-amino-5-(4-isopropyl-p...)
Affinity DataIC50:  6.48E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099859(CHEMBL29220 | Sodium; (E)-2-amino-5-(2-fluoro-phen...)
Affinity DataIC50:  8.02E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099882(CHEMBL29958 | Sodium; (Z)-2-amino-5-(4-isopropyl-p...)
Affinity DataIC50:  8.34E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099870(CHEMBL29022 | Sodium; (E)-2-amino-5-biphenyl-2-yl-...)
Affinity DataIC50:  8.92E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099884(CHEMBL29256 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  9.50E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099863(CHEMBL29023 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50:  9.56E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099861(CHEMBL28549 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099876(CHEMBL287626 | Sodium; (E)-2-amino-5-(4-cyano-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099869((E)-2-Amino-5-(2,4-difluoro-phenyl)-5-pyridin-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099877(CHEMBL29396 | Sodium; (E)-2-amino-5-biphenyl-4-yl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099885(CHEMBL281450 | Sodium; (E)-2-amino-5-biphenyl-4-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099868(CHEMBL27914 | Sodium; (E)-2-amino-5-biphenyl-3-yl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099883(CHEMBL28577 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099869((E)-2-Amino-5-(2,4-difluoro-phenyl)-5-pyridin-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099881((E)-2-Amino-5-(4-tert-butyl-phenyl)-5-(2,4-difluor...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099860(CHEMBL416203 | Sodium; (Z)-2-amino-5-(2,4-difluoro...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099866(CHEMBL418388 | Sodium; (E)-2-amino-5-(3,4-diethyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099880(CHEMBL29279 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099862(CHEMBL28746 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099871(CHEMBL286706 | Sodium; (E)-2-amino-5-(4-tert-butyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099879(CHEMBL28601 | Sodium; (E)-2-amino-5-(2,4-difluoro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099865(CHEMBL283017 | Sodium; 2-amino-5,5-bis-(4-isopropy...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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