Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50035142
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102078BDBM50102078(N-{2-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102091BDBM50102091(1-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-qui...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102088BDBM50102088(1-[Bis-(2-hydroxy-ethyl)-amino]-3-[4-(3-chloro-4-f...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102093BDBM50102093(6,7-dimethoxy-N-m-tolylquinazolin-4-amine | (6,7-D...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102085BDBM50102085(1-Amino-3-[4-(3-chloro-4-fluoro-phenylamino)-7-met...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102080BDBM50102080((3-Chloro-4-fluoro-phenyl)-[6-(2-dimethylamino-eth...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102069BDBM50102069((3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-methyla...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102071BDBM50102071(1-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-qui...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102081BDBM50102081((3-Chloro-4-fluoro-phenyl)-{7-methoxy-6-[2-(2-meth...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4626BDBM4626(CHEMBL301018 | N-(3-chloro-4-fluorophenyl)-6,7-dim...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102083BDBM50102083((3-Chloro-4-fluoro-phenyl)-{7-methoxy-6-[2-(4-meth...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451193BDBM50451193(CHEMBL14699)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102082BDBM50102082(2-[{2-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102070BDBM50102070((3-Chloro-4-fluoro-phenyl)-[6-(3-dimethylamino-pro...)
Affinity DataIC50: 49nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102074BDBM50102074((3-Chloro-4-fluoro-phenyl)-[6-(3-diethylamino-prop...)
Affinity DataIC50: 57nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102087BDBM50102087((6-{2-[Bis-(2-methoxy-ethyl)-amino]-ethoxy}-7-meth...)
Affinity DataIC50: 61nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102094BDBM50102094((3-Chloro-4-fluoro-phenyl)-[6-(2-imidazol-1-yl-eth...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366684BDBM50366684(CHEMBL1788321)
Affinity DataIC50: 67nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102075BDBM50102075(2-{2-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-...)
Affinity DataIC50: 69nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102079BDBM50102079((3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-pyrroli...)
Affinity DataIC50: 71nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102072BDBM50102072((3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-piperid...)
Affinity DataIC50: 79nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102089BDBM50102089((3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-pyrroli...)
Affinity DataIC50: 87nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102086BDBM50102086((3-Chloro-4-fluoro-phenyl)-[6-(2-diethylamino-etho...)
Affinity DataIC50: 93nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366685BDBM50366685(CHEMBL1744086)
Affinity DataIC50: 95nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102077BDBM50102077((3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-piperid...)
Affinity DataIC50: 98nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102084BDBM50102084([6-(2-tert-Butylamino-ethoxy)-7-methoxy-quinazolin...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102076BDBM50102076((3-Chloro-4-fluoro-phenyl)-[6-(2-isopropylamino-et...)
Affinity DataIC50: 310nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed