Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50011092
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102217BDBM50102217(3-[5-(4-Fluoro-phenylcarbamoyl)-1-oxy-pyridine-2-s...)
Affinity DataIC50: 32nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102229BDBM50102229(6-Benzenesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicoti...)
Affinity DataIC50: 90nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102225BDBM50102225(N'-(3-[2,2']Bithiophenyl-5-yl-6,7-dichloro-quinoxa...)
Affinity DataIC50: 110nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102219BDBM50102219(N-(4-Fluoro-phenyl)-6-methanesulfonyl-1-oxy-nicoti...)
Affinity DataIC50: 130nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102216BDBM50102216(6-Ethanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotin...)
Affinity DataIC50: 130nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102226BDBM50102226(N-(4-Fluoro-phenyl)-1-oxy-6-phenylmethanesulfonyl-...)
Affinity DataIC50: 280nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102218BDBM50102218(N-(4-Fluoro-phenyl)-1-oxy-6-(propane-2-sulfonyl)-n...)
Affinity DataIC50: 400nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102230BDBM50102230(6-Cyclopentanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-n...)
Affinity DataIC50: 460nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102221BDBM50102221(6-Chloro-N-(4-fluoro-phenyl)-1-oxy-nicotinamide | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102224BDBM50102224(6-Chloro-N-(4-iodo-phenyl)-1-oxy-nicotinamide | CH...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102227BDBM50102227(6-Chloro-N-cyclohexyl-1-oxy-nicotinamide | CHEMBL6...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102228BDBM50102228(N-Benzhydryl-6-chloro-1-oxy-nicotinamide | CHEMBL6...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102220BDBM50102220(N-(4-tert-Butyl-phenyl)-6-chloro-1-oxy-nicotinamid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102223BDBM50102223(6-Chloro-N-(4-methoxy-phenyl)-1-oxy-nicotinamide |...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102215BDBM50102215(6-Chloro-N-(2-hydroxy-phenyl)-1-oxy-nicotinamide |...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Celltech R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102214BDBM50102214(6-Chloro-N-(4-fluoro-benzyl)-1-oxy-nicotinamide | ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]IL-8 and membranes prepared from Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed