Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50011129
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102687(4-Butoxy-N-(1-dimethylamino-cyclopentylmethyl)-3,5...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102688(4-Benzyloxy-N-(1-dimethylamino-cyclohexylmethyl)-3...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of human Glycine Transporter type-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102687(4-Butoxy-N-(1-dimethylamino-cyclopentylmethyl)-3,5...)
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of human Glycine Transporter type-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102685(4-Butoxy-N-(1-dimethylamino-cyclohexylmethyl)-3,5-...)
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of human Glycine Transporter type-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102688(4-Benzyloxy-N-(1-dimethylamino-cyclohexylmethyl)-3...)
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of human Glycine Transporter type-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102685(4-Butoxy-N-(1-dimethylamino-cyclohexylmethyl)-3,5-...)
Affinity DataIC50:  214nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102689(4-Butoxy-N-(2-dimethylamino-2-phenyl-ethyl)-3,5-di...)
Affinity DataIC50:  566nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102686(4-Butoxy-N-(2-dimethylamino-2-methyl-propyl)-3,5-d...)
Affinity DataIC50:  696nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102694(4-Butoxy-N-[1-(ethyl-methyl-amino)-cyclohexylmethy...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102696(4-Butoxy-3,5-dimethoxy-N-(1-piperidin-1-yl-cyclohe...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102691(CHEMBL89571 | N-(1-Dimethylamino-cyclohexylmethyl)...)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102690(4-Butoxy-N-(1-dimethylamino-cyclohexylmethyl)-3-me...)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102695(4-Butoxy-N-(1-dimethylamino-cyclohexylmethyl)-benz...)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50102693(CHEMBL91900 | N-(1-Dimethylamino-cyclohexylmethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed