Compile Data Set for Download or QSAR
maximum 50k data
Found 86 Enz. Inhib. hit(s) with all data for entry = 50011156
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103034((S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2,6-dichlor...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103015((S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103015((S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103029((S)-6-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103014((S)-2-[(S)-2-{3-[1-(4-Fluoro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103038((S)-2-[(S)-2-{3-[1-(2-Chloro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103025((S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3...)
Affinity DataIC50:  150nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103016(4-Amino-N-benzyl-2-[(S)-2-{3-[1-(2,6-dichloro-benz...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103016(4-Amino-N-benzyl-2-[(S)-2-{3-[1-(2,6-dichloro-benz...)
Affinity DataIC50:  160nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103017((S)-N-[1-Benzylcarbamoyl-2-(3H-imidazol-4-yl)-ethy...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103024((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103020((S)-2-[(S)-2-{3-[3-Diethylaminomethyl-1-(3-methyl-...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103018((S)-2-[(S)-2-{3-[3-Diethylaminomethyl-1-(2-methyl-...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103036(2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  240nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103036(2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  240nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098218((S)-2-[(S)-2-{3-[1-(4-Fluoro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103036(2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103026((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103016(4-Amino-N-benzyl-2-[(S)-2-{3-[1-(2,6-dichloro-benz...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103038((S)-2-[(S)-2-{3-[1-(2-Chloro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  380nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103028(CHEMBL305188 | N-Benzyl-2-[(S)-2-{3-[1-(2,6-dichlo...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103028(CHEMBL305188 | N-Benzyl-2-[(S)-2-{3-[1-(2,6-dichlo...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103037((S)-2-[(S)-2-{3-[3-Azetidin-1-ylmethyl-1-(4-fluoro...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103017((S)-N-[1-Benzylcarbamoyl-2-(3H-imidazol-4-yl)-ethy...)
Affinity DataIC50:  460nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103017((S)-N-[1-Benzylcarbamoyl-2-(3H-imidazol-4-yl)-ethy...)
Affinity DataIC50:  460nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103015((S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50:  500nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103021((S)-N-(2-Amino-1-benzylcarbamoyl-ethyl)-2-{3-[1-(2...)
Affinity DataIC50:  500nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098212((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...)
Affinity DataIC50:  570nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098212((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...)
Affinity DataIC50:  570nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103035((S)-2-[(S)-2-{3-[1-(4-Fluoro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  600nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103033((S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2-methyl-be...)
Affinity DataIC50:  600nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103033((S)-2-((S)-3-(4-Cyano-phenyl)-2-{3-[1-(2-methyl-be...)
Affinity DataIC50:  620nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103029((S)-6-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103029((S)-6-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103026((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  730nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103025((S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3...)
Affinity DataIC50:  800nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098212((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...)
Affinity DataIC50:  820nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098211((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098211((S)-2-[(S)-2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrroli...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103021((S)-N-(2-Amino-1-benzylcarbamoyl-ethyl)-2-{3-[1-(2...)
Affinity DataIC50:  900nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103030((S)-2-[(S)-2-{3-[3-Diethylaminomethyl-1-(4-fluoro-...)
Affinity DataIC50:  900nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103022((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103030((S)-2-[(S)-2-{3-[3-Diethylaminomethyl-1-(4-fluoro-...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103021((S)-N-(2-Amino-1-benzylcarbamoyl-ethyl)-2-{3-[1-(2...)
Affinity DataIC50:  920nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103027((S)-2-[(S)-2-{3-[1-(4-Fluoro-benzyl)-3-piperidin-1...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103024((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103024((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103014((S)-2-[(S)-2-{3-[1-(4-Fluoro-benzyl)-3-pyrrolidin-...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103020((S)-2-[(S)-2-{3-[3-Diethylaminomethyl-1-(3-methyl-...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103025((S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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