Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50011168
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218779(CHEMBL306899)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218777(CHEMBL66626)
Affinity DataKi:  92nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50080029(4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...)
Affinity DataKi:  180nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218774(CHEMBL68831)
Affinity DataKi:  305nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218782(CHEMBL70615)
Affinity DataKi:  305nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218781(CHEMBL69219)
Affinity DataKi:  610nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218780(CHEMBL302292)
Affinity DataKi:  2.44E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218778(CHEMBL65954)
Affinity DataKi:  4.51E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218775(CHEMBL69429)
Affinity DataKi:  5.61E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50218776(CHEMBL68881)
Affinity DataKi:  5.92E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103133(1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataKi:  7.30E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]-prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103131(1-[(S)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataKi:  7.30E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]-prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103133(1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataIC50:  19nMAssay Description:Evaluated for in vitro inhibition of recombinant rat NR1C/2B receptor expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103133(1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Evaluated for in vitro inhibition of recombinant rat NR1C/2A receptor expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed