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Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50036961
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing each of the cloned human SRIF receptor (sst-2) subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataKi:  0.790nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369893(CHEMBL1201959)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103421(1,1-Dibutyl-6-chloro-3-(4-phenyl-1H-imidazol-2-yl)...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataKi:  3.40nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Affinity DataKi:  6nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103425(6-Methyl-1,1-dipentyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103433(1,1-Diethyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-...)
Affinity DataKi:  11nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103432(1-Pentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-tet...)
Affinity DataKi:  11nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103415(3-(4-phenyl-1H-2-imidazolyl)-(3S)-spiro[2,3,4,9-te...)
Affinity DataKi:  13nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103420(6-Benzyloxy-1,1-dibutyl-3-(4-phenyl-1H-imidazol-2-...)
Affinity DataKi:  17nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103427(1,1-Dihexyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-...)
Affinity DataKi:  28nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103429(CHEMBL321066 | Dimethyl-{4-[3-(4-phenyl-1H-imidazo...)
Affinity DataKi:  33nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103424(1-(4-Methoxy-phenyl)-3-(4-phenyl-1H-imidazol-2-yl)...)
Affinity DataKi:  60nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369894(CHEMBL1202953)
Affinity DataKi:  84nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103419(1-(2-Nitro-phenyl)-3-(4-phenyl-1H-imidazol-2-yl)-2...)
Affinity DataKi:  200nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103426(3-(4-Phenyl-1H-imidazol-2-yl)-1-pyridin-4-yl-2,3,4...)
Affinity DataKi:  320nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103428(1,1-Dibutyl-3-(4-phenyl-1H-imidazol-2-yl)-1,2,3,4-...)
Affinity DataKi:  430nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103434(1-Cyclohexyl-3-(4-phenyl-1H-imidazol-2-yl)-9H-beta...)
Affinity DataKi:  750nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369893(CHEMBL1201959)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-5) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369891(CHEMBL1202952)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103435(1,1-Dibutyl-3-(4,5-diphenyl-1H-imidazol-2-yl)-2,3,...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369893(CHEMBL1201959)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369893(CHEMBL1201959)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-5) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 1(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369893(CHEMBL1201959)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-5) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-5) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataIC50:  0.840nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103414(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  5.40nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369890(CHEMBL1237140 | CHEMBL1788167)
Affinity DataIC50:  6.80nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50369893(CHEMBL1201959)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103421(1,1-Dibutyl-6-chloro-3-(4-phenyl-1H-imidazol-2-yl)...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103425(6-Methyl-1,1-dipentyl-3-(4-phenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed