Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50011490
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107083BDBM50107083([5-(2,4-Dichloro-phenyl)-1-methyl-1H-[1,2,4]triazo...)
Affinity DataKi:  9nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107086BDBM50107086([5-(4-Bromo-2-methyl-phenyl)-1-methyl-1H-[1,2,4]tr...)
Affinity DataKi:  10nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107078BDBM50107078(2-[5-(2,4-Dichloro-phenyl)-3-dipropylamino-[1,2,4]...)
Affinity DataKi:  14nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107085BDBM50107085([5-(2,4-Dichloro-5-fluoro-phenyl)-1-methyl-1H-[1,2...)
Affinity DataKi:  15nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107074BDBM50107074([5-(4-Chloro-2-methyl-phenyl)-1-methyl-1H-[1,2,4]t...)
Affinity DataKi:  22nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107069BDBM50107069([5-(4-Chloro-2-methoxy-phenyl)-1-methyl-1H-[1,2,4]...)
Affinity DataKi:  26nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107080BDBM50107080([5-(4-Chloro-phenyl)-1-methyl-1H-[1,2,4]triazol-3-...)
Affinity DataKi:  33nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107076BDBM50107076(Dicyclopropylmethyl-[5-(2,4-dimethyl-phenyl)-1-met...)
Affinity DataKi:  72nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107084BDBM50107084([5-(2,4-Dichloro-phenyl)-1-ethyl-1H-[1,2,4]triazol...)
Affinity DataKi:  80nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107071BDBM50107071(Dicyclopropylmethyl-[1-methyl-5-(2,4,6-trimethyl-p...)
Affinity DataKi:  120nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107072BDBM50107072(Dicyclopropylmethyl-[1-ethyl-5-(2,4,6-trimethyl-ph...)
Affinity DataKi:  310nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107081BDBM50107081(Dicyclopropylmethyl-propyl-[1-(2,2,2-trifluoro-eth...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107070BDBM50107070([1-Allyl-5-(2,4,6-trimethyl-phenyl)-1H-[1,2,4]tria...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107075BDBM50107075([5-(2,4-Dichloro-phenyl)-2H-[1,2,4]triazol-3-yl]-d...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107079BDBM50107079([5-(2,4-Dichloro-phenyl)-1-methyl-1H-[1,2,4]triazo...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107068BDBM50107068(Dicyclopropylmethyl-propyl-[5-(2,4,6-trimethyl-phe...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107073BDBM50107073([5-(2,4-Dichloro-phenyl)-1-methyl-1H-[1,2,4]triazo...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107077BDBM50107077(Cyclopropylmethyl-[5-(2,4-dichloro-phenyl)-1-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107082BDBM50107082([5-(2,4-Dichloro-phenyl)-2-methyl-2H-[1,2,4]triazo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]o-CRF binding to human Corticotropin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed