Compile Data Set for Download or QSAR
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Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50011498
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107174(1-{3-[4-(2-Methoxy-phenylsulfanyl)-2,3-bis-trifluo...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(2-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107168(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(0.03-0.5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107166(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  2nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107168(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(3-6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107176(1-{3-[2,3-Dichloro-4-(1-methyl-1H-indol-5-ylsulfan...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (1-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107173(1-{3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trif...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107166(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (4-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107162(3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trifluo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (3-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(3-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107174(1-{3-[4-(2-Methoxy-phenylsulfanyl)-2,3-bis-trifluo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(4-6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(5-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107176(1-{3-[2,3-Dichloro-4-(1-methyl-1H-indol-5-ylsulfan...)
Affinity DataIC50:  6nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107164(3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107167(1-{3-[2,3-Dichloro-4-(2,3-dihydro-benzo[1,4]dioxin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107181(1-{3-[2,3-Dichloro-4-(2-isopropyl-phenylsulfanyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (3-18)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107173(1-{3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trif...)
Affinity DataIC50:  6nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (5-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107161(1-(4-Acetyl-piperazin-1-yl)-3-[2,3-dichloro-4-(2,3...)
Affinity DataIC50:  7nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(6-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107167(1-{3-[2,3-Dichloro-4-(2,3-dihydro-benzo[1,4]dioxin...)
Affinity DataIC50:  7nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107171(1-{3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107161(1-(4-Acetyl-piperazin-1-yl)-3-[2,3-dichloro-4-(2,3...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (6-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107171(1-{3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-30)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107162(3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trifluo...)
Affinity DataIC50:  8nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107164(3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-pheny...)
Affinity DataIC50:  10nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(6-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107181(1-{3-[2,3-Dichloro-4-(2-isopropyl-phenylsulfanyl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-19)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107187(3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-3...)
Affinity DataIC50:  30nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(30-30)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092956(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-isopropyl-phen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(12-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098770((E)-1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,3...)
Affinity DataIC50:  40nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(30-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107182(3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-phenyl]-1...)
Affinity DataIC50:  40nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (6-100)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092956(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-isopropyl-phen...)
Affinity DataIC50:  44nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(30-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103295(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(40-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107160(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benz...)
Affinity DataIC50:  55nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(50-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107160(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benz...)
Affinity DataIC50:  60nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (30-170)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098770((E)-1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,3...)
Affinity DataIC50:  80nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (30-150)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107184(3-[4-(2-Methoxy-phenylsulfanyl)-2,3-dimethyl-pheny...)
Affinity DataIC50:  90nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (80-110)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092928(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dichloro-phe...)
Affinity DataIC50:  100nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(30-300)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092928(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dichloro-phe...)
Affinity DataIC50:  105nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(100-110)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107186(1-{3-[5,6-Difluoro-4-(2-isopropyl-phenylsulfanyl)-...)
Affinity DataIC50:  115nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(110-120)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092943(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,4-dic...)
Affinity DataIC50:  130nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (100-600)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107189(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benz...)
Affinity DataIC50:  139nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(120-140)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092943(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,4-dic...)
Affinity DataIC50:  140nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(100-200)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107175(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  145nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(140-150)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107182(3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-phenyl]-1...)
Affinity DataIC50:  150nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(130-170)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107180(1-{3-[4-(2-Methoxy-phenylsulfanyl)-2-trifluorometh...)
Affinity DataIC50:  265nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (260-270)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107170(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50:  295nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (290-300)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107188(1-{3-[2-Chloro-4-(2-methoxy-phenylsulfanyl)-phenyl...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(760-2620)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107178(5-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-2-(...)
Affinity DataIC50:  3.75E+3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(3700-3800)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107185(1-(4-Acetyl-piperazin-1-yl)-3-[2-fluoro-4-(2-metho...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (2500-11500)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107179(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,4-dichloro-phe...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (3600-5100)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107159(3-[4-(2,3-Dichloro-phenylsulfanyl)-phenyl]-1-morph...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-L(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107183(1-(4-Acetyl-piperazin-1-yl)-3-[3-methoxy-4-(2-meth...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(10400-11300)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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