Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50011522
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107530(4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107522(4-(5-Chloro-thiophen-2-yl)-5-(4-methanesulfonyl-ph...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107526(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-(5-methyl-...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107515(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107519(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-methyl...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107516(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-phenyl-oxa...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107529(4-(5-Ethyl-thiophen-2-yl)-5-(4-methanesulfonyl-phe...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107521(4-Cyclohexyl-2-ethyl-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107514(4-Cycloheptyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107530(4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107524(5-(5-Chloro-thiophen-2-yl)-4-(4-methanesulfonyl-ph...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107518(5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107517(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-N-methyl-ben...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  4.70E+3nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107522(4-(5-Chloro-thiophen-2-yl)-5-(4-methanesulfonyl-ph...)
Affinity DataIC50:  1.25E+4nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107523(4-Cyclopentyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50:  1.80E+4nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107525(5-(4-Ethanesulfonyl-phenyl)-4-(4-fluoro-phenyl)-2-...)
Affinity DataIC50:  3.80E+4nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107515(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50:  4.20E+4nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50:  4.75E+4nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107526(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-(5-methyl-...)
Affinity DataIC50:  4.75E+4nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107521(4-Cyclohexyl-2-ethyl-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50:  6.00E+4nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107524(5-(5-Chloro-thiophen-2-yl)-4-(4-methanesulfonyl-ph...)
Affinity DataIC50:  9.30E+4nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107518(5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107520(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-phenyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107519(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107514(4-Cycloheptyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107525(5-(4-Ethanesulfonyl-phenyl)-4-(4-fluoro-phenyl)-2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107520(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-phenyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107517(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-N-methyl-ben...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107523(4-Cyclopentyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107516(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-phenyl-oxa...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107529(4-(5-Ethyl-thiophen-2-yl)-5-(4-methanesulfonyl-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed