Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50011575
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108204BDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50: 0.550nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108202BDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108192BDBM50108192(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-b...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108194BDBM50108194(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulf...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108187BDBM50108187(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108185BDBM50108185(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesul...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108193BDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108196BDBM50108196(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108191BDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108203BDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108195BDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108200BDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108197BDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108202BDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)
Affinity DataIC50: 16nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108188BDBM50108188(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hydroxymethyl-1-me...)
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451439BDBM50451439(CHEMBL2114305)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108198BDBM50108198(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108190BDBM50108190(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 31nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108207BDBM50108207(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108187BDBM50108187(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 34nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108205BDBM50108205(N-{2-Benzo[1,3]dioxol-5-yl-2-[1-methyl-6-(1H-tetra...)
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108199BDBM50108199(N-[2-(6-Aminomethyl-1-methyl-1H-indol-3-yl)-2-benz...)
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108201BDBM50108201(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-cyano-1-methyl-1H-...)
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108196BDBM50108196(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 68nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108189BDBM50108189(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 72nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108185BDBM50108185(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesul...)
Affinity DataIC50: 94nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108206BDBM50108206(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108199BDBM50108199(N-[2-(6-Aminomethyl-1-methyl-1H-indol-3-yl)-2-benz...)
Affinity DataIC50: 204nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108198BDBM50108198(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 210nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108186BDBM50108186(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108195BDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)
Affinity DataIC50: 228nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108192BDBM50108192(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-b...)
Affinity DataIC50: 302nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108191BDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)
Affinity DataIC50: 310nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108204BDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50: 397nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108188BDBM50108188(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hydroxymethyl-1-me...)
Affinity DataIC50: 450nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108189BDBM50108189(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 474nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108194BDBM50108194(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulf...)
Affinity DataIC50: 774nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108193BDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)
Affinity DataIC50: 846nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108203BDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)
Affinity DataIC50: 1.06E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108200BDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451439BDBM50451439(CHEMBL2114305)
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108207BDBM50108207(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50: 2.20E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108197BDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50: 2.57E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed