Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50011577
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108208BDBM50108208((S)-2-{[(2S,3S)-1-(3,5-Dichloro-benzenesulfonyl)-3...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108215BDBM50108215((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(2S,3S)-1-(3,5-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108213BDBM50108213((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108212BDBM50108212((S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108217BDBM50108217((S)-2-[((S)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108216BDBM50108216((S)-2-[((R)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105393BDBM50105393((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(S)-1-(3,5-dich...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105380BDBM50105380((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108211BDBM50108211((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108213BDBM50108213((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108214BDBM50108214((S)-2-{[(S)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50: 6nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108210BDBM50108210((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((S)-thiazolid...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108217BDBM50108217((S)-2-[((S)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108209BDBM50108209((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((R)-thiazolid...)
Affinity DataIC50: 13nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108216BDBM50108216((S)-2-[((R)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108215BDBM50108215((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(2S,3S)-1-(3,5-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108211BDBM50108211((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108208BDBM50108208((S)-2-{[(2S,3S)-1-(3,5-Dichloro-benzenesulfonyl)-3...)
Affinity DataIC50: 53nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105393BDBM50105393((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(S)-1-(3,5-dich...)
Affinity DataIC50: 89nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105380BDBM50105380((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50: 102nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108214BDBM50108214((S)-2-{[(S)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50: 160nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108210BDBM50108210((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((S)-thiazolid...)
Affinity DataIC50: 197nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108212BDBM50108212((S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50: 306nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108209BDBM50108209((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((R)-thiazolid...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed