Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50042173
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108227BDBM50108227((S)-2-[((R)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 0.370nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108219BDBM50108219((5S,8R,13R,15aS)-8-[(S)-2-Acetylamino-3-(4-hydroxy...)
Affinity DataIC50: 2nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108230BDBM50108230((S)-3-[4-(4-Benzoyl-piperazine-1-carbonyl)-phenyl]...)
Affinity DataIC50: 3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108221BDBM50108221((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108231BDBM50108231((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108222BDBM50108222((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 4nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108218BDBM50108218((S)-3-[4-(2-Acetyl-phenylcarbamoyl)-phenyl]-2-[((S...)
Affinity DataIC50: 4nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108223BDBM50108223((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 5nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108233BDBM50108233((S)-3-{4-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 6.5nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108236BDBM50108236((S)-3-[4-(4-Acetyl-piperazine-1-carbonyl)-phenyl]-...)
Affinity DataIC50: 7nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108232BDBM50108232((S)-3-[4-(4-Benzenesulfonyl-piperazine-1-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108225BDBM50108225((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 12nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108227BDBM50108227((S)-2-[((R)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 12nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108235BDBM50108235((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 27nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108226BDBM50108226((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 57nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108228BDBM50108228((S)-3-[3-(4-Benzenesulfonyl-piperazine-1-carbonyl)...)
Affinity DataIC50: 60nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108229BDBM50108229((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 61nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108220BDBM50108220((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 73nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108234BDBM50108234((S)-3-[3-(4-Benzoyl-piperazine-1-carbonyl)-phenyl]...)
Affinity DataIC50: 120nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108219BDBM50108219((5S,8R,13R,15aS)-8-[(S)-2-Acetylamino-3-(4-hydroxy...)
Affinity DataIC50: 200nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108224BDBM50108224((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 240nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108222BDBM50108222((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 320nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108221BDBM50108221((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 470nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108223BDBM50108223((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 550nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108218BDBM50108218((S)-3-[4-(2-Acetyl-phenylcarbamoyl)-phenyl]-2-[((S...)
Affinity DataIC50: 940nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108230BDBM50108230((S)-3-[4-(4-Benzoyl-piperazine-1-carbonyl)-phenyl]...)
Affinity DataIC50: 960nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108231BDBM50108231((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 1.70E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108233BDBM50108233((S)-3-{4-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 2.10E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108232BDBM50108232((S)-3-[4-(4-Benzenesulfonyl-piperazine-1-carbonyl)...)
Affinity DataIC50: 2.20E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108236BDBM50108236((S)-3-[4-(4-Acetyl-piperazine-1-carbonyl)-phenyl]-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108220BDBM50108220((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 7.80E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108225BDBM50108225((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 9.53E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108224BDBM50108224((S)-2-[((S)-1-Benzyl-5-oxo-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 2.44E+4nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed