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Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 50037068
TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108575(3-(4-Iodo-benzenesulfonylamino)-N-(5-sulfamoyl-[1,...)
Affinity DataKi:  1.20nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108585(3-[4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM16669(CHEMBL281376 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-y...)
Affinity DataKi:  2nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108577(5-(3-(4-methyl-sulfonylbenzene)-ureido)-[1,3,4]thi...)
Affinity DataKi:  3nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11427(2-N-(4-methylbenzene)-1,3,4-thiadiazole-2,5-disulf...)
Affinity DataKi:  3nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11427(2-N-(4-methylbenzene)-1,3,4-thiadiazole-2,5-disulf...)
Affinity DataKi:  4nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108585(3-[4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)...)
Affinity DataKi:  4nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108577(5-(3-(4-methyl-sulfonylbenzene)-ureido)-[1,3,4]thi...)
Affinity DataKi:  4nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108567(5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...)
Affinity DataKi:  5nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11427(2-N-(4-methylbenzene)-1,3,4-thiadiazole-2,5-disulf...)
Affinity DataKi:  5nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  5nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108585(3-[4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)...)
Affinity DataKi:  5.5nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108579(2-Propyl-pentanoic acid (5-sulfamoyl-[1,3,4]thiadi...)
Affinity DataKi:  6nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108567(5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...)
Affinity DataKi:  6nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108567(5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...)
Affinity DataKi:  7nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108578(2-Propyl-pentanoic acid (2-sulfamoyl-benzothiazol-...)
Affinity DataKi:  7nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108571(2-Propyl-pentanoic acid 2-(2-sulfamoyl-benzothiazo...)
Affinity DataKi:  7nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108565(2-Propyl-pentanoic acid 2-sulfamoyl-benzothiazol-6...)
Affinity DataKi:  7nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM16668(2,2-dimethyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  9nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108583(2-Propyl-pentanoic acid [2-(5-sulfamoyl-[1,3,4]thi...)
Affinity DataKi:  9nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108572((5-Sulfamoyl-[1,3,4]thiadiazol-2-yl)-carbamic acid...)
Affinity DataKi:  9nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108563(Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]t...)
Affinity DataKi:  10nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB


TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108589(3,4,5-Trimethoxy-N-(5-sulfamoyl-[1,3,4]thiadiazol-...)
Affinity DataKi:  10nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108586(2-Propyl-pentanoic acid (3-methyl-5-sulfamoyl-3H-[...)
Affinity DataKi:  10nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  12nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108577(5-(3-(4-methyl-sulfonylbenzene)-ureido)-[1,3,4]thi...)
Affinity DataKi:  12nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108571(2-Propyl-pentanoic acid 2-(2-sulfamoyl-benzothiazo...)
Affinity DataKi:  13nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)
Affinity DataKi:  14nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108565(2-Propyl-pentanoic acid 2-sulfamoyl-benzothiazol-6...)
Affinity DataKi:  15nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108578(2-Propyl-pentanoic acid (2-sulfamoyl-benzothiazol-...)
Affinity DataKi:  16nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM16669(CHEMBL281376 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-y...)
Affinity DataKi:  21nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108579(2-Propyl-pentanoic acid (5-sulfamoyl-[1,3,4]thiadi...)
Affinity DataKi:  25nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108564(2-Propyl-pentanoic acid (2,3-dichloro-4,6-disulfam...)
Affinity DataKi:  26nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108588(2-Propyl-pentanoic acid (2-bromo-4-sulfamoyl-pheny...)
Affinity DataKi:  36nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM16669(CHEMBL281376 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-y...)
Affinity DataKi:  38nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108586(2-Propyl-pentanoic acid (3-methyl-5-sulfamoyl-3H-[...)
Affinity DataKi:  42nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108580(2-Propyl-pentanoic acid (2-iodo-4-sulfamoyl-phenyl...)
Affinity DataKi:  43nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108569(2-Propyl-pentanoic acid (2-fluoro-4-sulfamoyl-phen...)
Affinity DataKi:  45nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM16668(2,2-dimethyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  46nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108588(2-Propyl-pentanoic acid (2-bromo-4-sulfamoyl-pheny...)
Affinity DataKi:  49nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108579(2-Propyl-pentanoic acid (5-sulfamoyl-[1,3,4]thiadi...)
Affinity DataKi:  50nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108573(2-Propyl-pentanoic acid (2-chloro-4-sulfamoyl-phen...)
Affinity DataKi:  50nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108571(2-Propyl-pentanoic acid 2-(2-sulfamoyl-benzothiazo...)
Affinity DataKi:  50nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108565(2-Propyl-pentanoic acid 2-sulfamoyl-benzothiazol-6...)
Affinity DataKi:  50nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108589(3,4,5-Trimethoxy-N-(5-sulfamoyl-[1,3,4]thiadiazol-...)
Affinity DataKi:  51nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  54nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108578(2-Propyl-pentanoic acid (2-sulfamoyl-benzothiazol-...)
Affinity DataKi:  62nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108563(Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]t...)
Affinity DataKi:  65nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108584(2-Propyl-pentanoic acid (5-chloro-2,4-disulfamoyl-...)
Affinity DataKi:  70nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50108586(2-Propyl-pentanoic acid (3-methyl-5-sulfamoyl-3H-[...)
Affinity DataKi:  70nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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