Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50011675
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067485BDBM50067485(CHEMBL544440 | 3-[(Benzyl-methyl-amino)-methyl]-7-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human GnRH receptor using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109219BDBM50109219(4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against human GnRH receptor using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109219BDBM50109219(4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...)
Affinity DataIC50: 4nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099023BDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against human GnRH receptor using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109222BDBM50109222(8-Cyano-1-(2-fluoro-benzyl)-7-(4-isobutoxy-phenyl)...)
Affinity DataKi:  25nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109203BDBM50109203(8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...)
Affinity DataKi:  31nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109207BDBM50109207(8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...)
Affinity DataKi:  33nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067485BDBM50067485(CHEMBL544440 | 3-[(Benzyl-methyl-amino)-methyl]-7-...)
Affinity DataIC50: 60nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109211BDBM50109211(8-Cyano-1-(2-fluoro-benzyl)-7-(4-isobutoxy-phenyl)...)
Affinity DataKi:  100nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099023BDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 170nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109205BDBM50109205(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  180nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109212BDBM50109212(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  260nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109209BDBM50109209(8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...)
Affinity DataKi:  400nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109231BDBM50109231(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  400nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109227BDBM50109227(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  500nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109201BDBM50109201(8-Cyano-1-(2,6-difluoro-benzyl)-7-(4-isobutoxy-phe...)
Affinity DataKi:  800nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109226BDBM50109226(8-Cyano-1-(2,5-difluoro-benzyl)-7-(4-isobutoxy-phe...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109217BDBM50109217(6-[(Benzyl-methyl-amino)-methyl]-8-cyano-1-(2-fluo...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109214BDBM50109214(8-Cyano-1-(2,6-difluoro-benzyl)-7-(4-methoxy-pheny...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109230BDBM50109230(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109216BDBM50109216(8-Cyano-7-(4-isobutoxy-phenyl)-1-(2-methoxy-benzyl...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109224BDBM50109224(8-Cyano-1-(2,3-difluoro-benzyl)-7-(4-methoxy-pheny...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109213BDBM50109213(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109210BDBM50109210(1-Benzyl-8-cyano-7-(4-methoxy-phenyl)-6-{[methyl-(...)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109228BDBM50109228(8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-methoxy-pheny...)
Affinity DataKi:  3.70E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109218BDBM50109218(8-Cyano-1-(2-cyano-benzyl)-7-(4-methoxy-phenyl)-6-...)
Affinity DataKi:  4.90E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109221BDBM50109221(8-Cyano-1-(2,5-difluoro-benzyl)-7-(4-methoxy-pheny...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109220BDBM50109220(8-Cyano-1-(2-methoxy-benzyl)-7-(4-methoxy-phenyl)-...)
Affinity DataKi:  6.60E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109222BDBM50109222(8-Cyano-1-(2-fluoro-benzyl)-7-(4-isobutoxy-phenyl)...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109203BDBM50109203(8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...)
Affinity DataKi:  7.60E+3nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109205BDBM50109205(8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  7.70E+3nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109229BDBM50109229(1-(2-Chloro-benzyl)-8-cyano-7-(4-methoxy-phenyl)-6...)
Affinity DataKi:  8.50E+3nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109207BDBM50109207(8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109204BDBM50109204(8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109223BDBM50109223(1-Benzyl-6-[(benzyl-methyl-amino)-methyl]-8-cyano-...)
Affinity DataKi:  4.20E+4nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109225BDBM50109225(8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109206BDBM50109206(8-Cyano-1-cyclopropylmethyl-7-(4-methoxy-phenyl)-6...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109215BDBM50109215(1-Benzyl-8-cyano-6-dimethylaminomethyl-7-(4-methox...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109202BDBM50109202(8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed