Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50011723
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109771(3-{4-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109757(CHEMBL355937 | {2-[(1-{2-[1-(Benzooxazole-2-carbon...)
Affinity DataIC50:  7.20nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109765(CHEMBL357495 | [4-(1-{2-[1-(Benzooxazole-2-carbony...)
Affinity DataIC50:  7.40nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109777(CHEMBL118176 | {4-[((R)-1-{(S)-2-[(S)-1-(Benzooxaz...)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109761(2,2-Dimethyl-propionic acid (S)-2-{2-[((S)-1-{(S)-...)
Affinity DataIC50:  8.90nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109763(4-Carboxymethoxy-benzoic acid (1-{2-[1-(benzooxazo...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109756((4-{[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-p...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109759(CHEMBL358686 | N-(1-{2-[1-(Benzooxazole-2-carbonyl...)
Affinity DataIC50:  66nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109775(3-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-prop...)
Affinity DataIC50:  72nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109758(2,2-Dimethyl-propionic acid 2-{2-[2-(4-carboxymeth...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109769(2,2-Dimethyl-propionic acid 2-[2-({1-[2-(4-carboxy...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109755(2-[3-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-p...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109768(CHEMBL152728 | {4-[2-(2-{2-Methyl-1-[4-(3-methyl-b...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109772(2,2-Dimethyl-propionic acid 2-(2-benzyloxycarbonyl...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109770(CHEMBL345509 | {2-Methyl-1-[4-(3-methyl-butoxy)-be...)
Affinity DataIC50:  7.80E+3nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109776(CHEMBL152815 | [1-(4-Benzyloxy-benzooxazole-2-carb...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109778(CHEMBL347331 | [2-(2-Benzyloxycarbonylamino-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109773(CHEMBL358927 | [2-(2-Benzyloxycarbonylamino-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109774(CHEMBL152341 | [2-Methyl-1-(4-pentyloxy-benzooxazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109766(CHEMBL422507 | [1-(4-Ethoxy-benzooxazole-2-carbony...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109767(CHEMBL345261 | [1-(4-Hydroxy-benzooxazole-2-carbon...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109764(CHEMBL356913 | {2-Methyl-1-[4-(3-methyl-but-2-enyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109762(CHEMBL151907 | [1-(Benzooxazole-2-carbonyl)-2-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109760(CHEMBL356448 | {2-Methyl-1-[4-(3-trifluoromethyl-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109779(CHEMBL424148 | {1-[4-(2-Dimethylamino-ethoxy)-benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109754(CHEMBL151065 | {2-Methyl-1-[4-(1-phenyl-pentyloxy)...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109753(CHEMBL153315 | [1-(4-Carbamoylmethoxy-benzooxazole...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed