Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50011729
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  2.20nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291704((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  3.70nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  4.5nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  4.60nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291702((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  5nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  5.10nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  5.20nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291703((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  5.5nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291702((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  6nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291704((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  6.60nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291702((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  6.70nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291704((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  6.80nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291707((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  9.10nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291707((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291707((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291703((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291703((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  13nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  14nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291706((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291703((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  29nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  30nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291706((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  31nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291704((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  36nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291706((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  48nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291702((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  125nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291704((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  358nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  411nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291702((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  483nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  573nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291704((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  617nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291703((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291706((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291702((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291707((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291707((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  686nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291703((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291707((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291706((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi: >850nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291706((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >850nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >850nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed