Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50011740
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108325((S)-3-(4-tert-Butoxy-phenyl)-2-{[(S)-1-(3,5-dichlo...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108329((S)-3-(4-tert-Butoxy-phenyl)-2-{[(S)-1-(3,5-dichlo...)
Affinity DataIC50:  0.270nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109991((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109994((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.330nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108335((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.340nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108321((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.370nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109987((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.440nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109965((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.480nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109993((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.480nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105409((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109982((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  0.590nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105368((S)-3-Biphenyl-4-yl-2-{[(S)-1-(3,5-dichloro-benzen...)
Affinity DataIC50:  0.650nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109989((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.670nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109971((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.670nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109964((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.730nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109960((S)-3-(4-Cyano-phenyl)-2-{[(S)-1-(3,5-dichloro-ben...)
Affinity DataIC50:  0.790nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109979((S)-3-(4-Chloro-phenyl)-2-{[(S)-1-(3,5-dichloro-be...)
Affinity DataIC50:  0.850nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109957((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.860nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109973((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  0.860nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109981((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.860nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109992((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109959((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.920nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109961((S)-3-(4-Bromo-phenyl)-2-{[(S)-1-(3,5-dichloro-ben...)
Affinity DataIC50:  0.920nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109985((S)-3-(2-Chloro-phenyl)-2-{[(S)-1-(3,5-dichloro-be...)
Affinity DataIC50:  0.990nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109958((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109968((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109976((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109966((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109980((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109912((S)-2-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolidi...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109995((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109988((S)-3-(4-Cyano-phenyl)-2-{[(S)-1-(3,5-dichloro-ben...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109970((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109974((S)-3-(3-Chloro-phenyl)-2-{[(S)-1-(3,5-dichloro-be...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109969((S)-3-(2-Chloro-phenyl)-2-{[(S)-1-(3,5-dichloro-be...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109963((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109983((S)-3-(4-Chloro-phenyl)-2-{[(S)-1-(3,5-dichloro-be...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109986((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109978((S)-3-(3-Chloro-phenyl)-2-{[(S)-1-(3,5-dichloro-be...)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109967((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109984((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109990((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109972((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109977((R)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  152nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108329((S)-3-(4-tert-Butoxy-phenyl)-2-{[(S)-1-(3,5-dichlo...)
Affinity DataIC50:  646nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109975((S)-2-{[(R)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109957((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109964((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109959((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109958((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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