Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50037120
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110994(4-[2-Methyl-4-(5-methyl-thiophen-2-yl)-oxazol-5-yl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110998(2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-ox...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111000(2-Fluoro-4-[4-(4-fluoro-phenyl)-2-methyl-oxazol-5-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110999(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-fluoro-ben...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110995(4-(4-Cyclohexyl-2-ethyl-oxazol-5-yl)-2-fluoro-benz...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111004(4-(4-Cyclohexyl-2-isopropyl-oxazol-5-yl)-2-fluoro-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110996(2-Amino-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benz...)
Affinity DataIC50:  930nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110994(4-[2-Methyl-4-(5-methyl-thiophen-2-yl)-oxazol-5-yl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111003(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methyl-ben...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110993(2-Chloro-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111002(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-hydroxy-be...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110998(2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-ox...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111004(4-(4-Cyclohexyl-2-isopropyl-oxazol-5-yl)-2-fluoro-...)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111000(2-Fluoro-4-[4-(4-fluoro-phenyl)-2-methyl-oxazol-5-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110995(4-(4-Cyclohexyl-2-ethyl-oxazol-5-yl)-2-fluoro-benz...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50:  4.75E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110993(2-Chloro-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-ben...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111001(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110999(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-fluoro-ben...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110996(2-Amino-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111001(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111002(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-hydroxy-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111003(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methyl-ben...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed