Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50011849
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111398BDBM50111398((S)-2-(Isoxazole-4-sulfonylamino)-5-oxo-5-(2-pyrid...)
Affinity DataIC50: 2nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111419BDBM50111419(3-Oxo-3-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111404BDBM50111404(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50: 17nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111424BDBM50111424((S)-2-Butoxycarbonylamino-5-oxo-5-(2-pyridin-4-yl-...)
Affinity DataIC50: 17nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111418BDBM50111418(3-Oxo-3-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 25nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111401BDBM50111401((S)-2-Benzyloxycarbonylamino-5-oxo-5-(2-pyridin-4-...)
Affinity DataIC50: 25nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111432BDBM50111432([2-Oxo-4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]decan...)
Affinity DataIC50: 25nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111428BDBM50111428(7-Oxo-7-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-...)
Affinity DataIC50: 43nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111421BDBM50111421([5-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 47nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111405BDBM50111405(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50: 87nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111399BDBM50111399([4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 90nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111415BDBM50111415([1-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 106nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111427BDBM50111427(3-Oxo-3-[4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 113nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111429BDBM50111429([1-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 115nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111412BDBM50111412(3-Oxo-3-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 136nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111423BDBM50111423([1-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 138nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111411BDBM50111411([1-(8-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-2-ca...)
Affinity DataIC50: 153nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111409BDBM50111409(8-Oxo-8-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-...)
Affinity DataIC50: 196nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111414BDBM50111414(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50: 225nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111407BDBM50111407(3-[2-Oxo-4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 238nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111403BDBM50111403([4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 252nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111400BDBM50111400(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50: 254nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111431BDBM50111431([4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 320nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111425BDBM50111425(N-[1-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50: 447nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111406BDBM50111406([4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 688nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111430BDBM50111430([3-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 873nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111417BDBM50111417({Methyl-[1-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111413BDBM50111413(4-Oxo-4-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111420BDBM50111420(3-[5-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111408BDBM50111408(1-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111422BDBM50111422(5-[(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 1.19E+4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111410BDBM50111410(3-[(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 2.89E+4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111426BDBM50111426(6-[(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111416BDBM50111416(4-[(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-ca...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111402BDBM50111402(6-Oxo-6-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed