Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50035284
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataKi:  0.480nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111690(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  0.710nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111692(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111691(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataEC50:  1.90nMAssay Description:Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111692(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111690(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataEC50:  130nMAssay Description:Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111691(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataEC50:  935nMAssay Description:Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed