Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50011893
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111889BDBM50111889(1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.0770nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111893BDBM50111893(1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 0.0850nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111887BDBM50111887(1-{3-[4-((Z)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)
Affinity DataKi:  0.130nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111888BDBM50111888(1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.380nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111894BDBM50111894(1-{3-[4-((E)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)
Affinity DataKi:  0.570nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111881BDBM50111881(1-{3-[4-((E)-2-Iodo-vinyl)-phenyl]-8-aza-bicyclo[3...)
Affinity DataKi:  0.620nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111889BDBM50111889(1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataKi:  1.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111886BDBM50111886(1-[3-(3-Fluoro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 1.10nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111893BDBM50111893(1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  1.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111891BDBM50111891(1-[3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 1.70nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111891BDBM50111891(1-[3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  1.90nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111883BDBM50111883(1-[3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)
Affinity DataIC50: 2.20nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111883BDBM50111883(1-[3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)
Affinity DataKi:  2.40nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111890BDBM50111890(1-{8-((E)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)
Affinity DataKi:  2.80nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111886BDBM50111886(1-[3-(3-Fluoro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  7.30nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111888BDBM50111888(1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataKi:  9.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111880BDBM50111880(1-{8-((Z)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)
Affinity DataKi:  13nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111882BDBM50111882((E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 13nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111885BDBM50111885(1-[3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)
Affinity DataKi:  16nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111892BDBM50111892(1-[3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  20nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111885BDBM50111885(1-[3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]...)
Affinity DataIC50: 20nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451492BDBM50451492(CHEMBL2112943)
Affinity DataIC50: 47nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111882BDBM50111882((E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  51nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111881BDBM50111881(1-{3-[4-((E)-2-Iodo-vinyl)-phenyl]-8-aza-bicyclo[3...)
Affinity DataIC50: 51nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111892BDBM50111892(1-[3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 57nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111887BDBM50111887(1-{3-[4-((Z)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)
Affinity DataIC50: 67nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111894BDBM50111894(1-{3-[4-((E)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)
Affinity DataIC50: 401nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111890BDBM50111890(1-{8-((E)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)
Affinity DataIC50: 753nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451492BDBM50451492(CHEMBL2112943)
Affinity DataKi: >1.10E+3nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111880BDBM50111880(1-{8-((Z)-3-Iodo-allyl)-3-[4-(1-methyl-1H-pyrrol-2...)
Affinity DataIC50: 1.12E+3nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed