Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50042169 Sort by
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113539((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113546((S)-3-(2',6'-Dimethoxy-biphenyl-4-yl)-2-[((R)-2-me...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of I-VCAM-Ig binding to Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113526((S)-2-{[2-(3,5-Dichloro-benzenesulfonyl)-pyrazolid...)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113530((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(2-methyl-1,1-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113538((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(tetrahydro-fu...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113534((S)-2-[(1,1-Dioxo-tetrahydro-1lambda*6*-thiophene-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113532((S)-3-(2',6'-Dicyclopropoxy-biphenyl-4-yl)-2-[((R)...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113527((R)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((R)-2-methyl-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of I-VCAM-Ig binding to Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113542((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(5-oxo-pyrroli...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113537((S)-3-(2'-Cyclopropoxy-biphenyl-4-yl)-2-[((R)-2-me...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113543((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(2-methyl-tetr...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of I-VCAM-Ig binding to Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113528((S)-3-[4-(3-Benzyl-2-oxo-2,3-dihydro-imidazol-1-yl...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113533((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(tetrahydro-py...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113544((S)-3-(2'-Cyano-biphenyl-4-yl)-2-[((R)-2-methyl-te...)
Affinity DataIC50: 11nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113536((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((S)-pyrrolidi...)
Affinity DataIC50: 11nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113540((S)-2-[((R)-2-Methyl-tetrahydro-furan-2-carbonyl)-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113535((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((R)-2-methyl-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of I-VCAM-Ig binding to Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113529((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(pyrrolidine-1...)
Affinity DataIC50: 17nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113545((S)-2-[(4,5-Dihydro-pyrazole-1-carbonyl)-amino]-3-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113531((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[(tetrahydro-fu...)
Affinity DataIC50: 36nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113541((S)-2-(Cyclopentanecarbonyl-amino)-3-(2'-methoxy-b...)
Affinity DataIC50: 63nMAssay Description:Inhibition of very late antigen-4 alpha4-beta1 (VLA-4), I-VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed