Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 1063
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8552BDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50: 390nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8550BDBM8550(2-{[(3-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50: 820nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8555BDBM8555(methyl 3-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8541BDBM8541(N-[2-(2-fluorophenyl)ethyl]-2-[4-({[5-(pyridin-4-y...)
Affinity DataIC50: 1.20E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8554BDBM8554(2-{[(3-fluorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50: 1.40E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8548BDBM8548(cid_805390 | 2-(benzylsulfanyl)-5-(pyridin-4-yl)-1...)
Affinity DataIC50: 6.70E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8543BDBM8543(2-[4-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulf...)
Affinity DataIC50: 8.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8542BDBM8542(2-[4-({[5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl]sul...)
Affinity DataIC50: 1.10E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8551BDBM8551(2-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50: 1.20E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8547BDBM8547(4-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfany...)
Affinity DataIC50: 2.90E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8549BDBM8549(2-[(2-phenylethyl)sulfanyl]-5-(pyridin-4-yl)-1,3,4...)
Affinity DataIC50: 2.90E+4nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8553BDBM8553(2-{[(4-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50: 1.98E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8556BDBM8556(3-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfany...)
Affinity DataIC50: 2.35E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8557BDBM8557(2-({[3-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]methy...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8544BDBM8544(2-[4-({[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sul...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8545BDBM8545(2-[4-({[5-(pyridin-3-yl)-1,3,4-thiadiazol-2-yl]sul...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Novo Nordisk

LigandChemical structure of BindingDB Monomer ID 8546BDBM8546(2-[4-({[5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl]sul...)
Affinity DataIC50: 2.50E+5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed