Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50012035 Sort by
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113669(1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxyli...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human cathepsin K in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human cathepsin K in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113662(1-(2,3-Dichloro-phenyl)-1H-[1,2,4]triazole-3-carbo...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human cathepsin K in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113674(4-Methoxy-N-{(S)-1-[2-(4-methoxy-phenylamino)-ethy...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113673(4-Isopropyl-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113676({1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3-me...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113662(1-(2,3-Dichloro-phenyl)-1H-[1,2,4]triazole-3-carbo...)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113665([3-Methyl-1-(2-p-tolylamino-ethylcarbamoyl)-butyl]...)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113668({1-[2-(4-Chloro-phenylamino)-ethylcarbamoyl]-3-met...)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113675([3-Methyl-1-(2-m-tolylamino-ethylcarbamoyl)-butyl]...)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113671([3-Methyl-1-(2-phenylamino-ethylcarbamoyl)-butyl]-...)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113670({1-[2-(3-Chloro-phenylamino)-ethylcarbamoyl]-3-met...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113666({1-[2-(3-Methoxy-phenylamino)-ethylcarbamoyl]-3-me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant rabbit Cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113663(N-{1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113664(5-Isopropyl-pyridine-2-carboxylic acid {1-[2-(4-me...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113669(1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxyli...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113669(1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxyli...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113673(4-Isopropyl-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113664(5-Isopropyl-pyridine-2-carboxylic acid {1-[2-(4-me...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113662(1-(2,3-Dichloro-phenyl)-1H-[1,2,4]triazole-3-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113662(1-(2,3-Dichloro-phenyl)-1H-[1,2,4]triazole-3-carbo...)
Affinity DataKi:  11nMAssay Description:Eq. constant (Ki) for inhibition of Cathepsin K was determined by progress curves, following hydrolysis of Z-Phe-Arg- Amc in the absence and presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataKi:  15nMAssay Description:Eq. constant (Ki) for inhibition of Cathepsin K was determined by progress curves, following hydrolysis of Z-Phe-Arg- Amc in the absence and presence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed