Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50012044 Sort by
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113787(S-(2-{2-[2-(4-Carbamimidoyl-phenoxy)-ethyl]-piperi...)
Affinity DataKi:  0.370nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113790(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  0.530nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113791(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  0.800nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113785(RS-(2-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-et...)
Affinity DataKi:  0.960nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113799(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  1.10nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113794(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  1.30nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113802(5-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]...)
Affinity DataKi:  1.80nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113792(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  2.17nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Bovine)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113792(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory effect on plasmin in bovine plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Bovine)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113792(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  4.97nMAssay Description:Inhibitory effect on Coagulation factor Xa (FXa) from bovine plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113798(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  7.10nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113796(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  9.80nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113793(1-(2-Ethanesulfonylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataKi:  15nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113801(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  16nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113788(4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]...)
Affinity DataKi:  16nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113795(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  32nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113786(4-{2-[1-(2-Amino-3-phenyl-propionyl)-piperidin-2-y...)
Affinity DataKi:  56nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113787(S-(2-{2-[2-(4-Carbamimidoyl-phenoxy)-ethyl]-piperi...)
Affinity DataKi:  89nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113789(4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]...)
Affinity DataKi:  90nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113784(R-(2-{2-[2-(4-Carbamimidoyl-phenoxy)-ethyl]-piperi...)
Affinity DataKi:  120nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113785(RS-(2-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-et...)
Affinity DataKi:  370nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113800(RS-(1-Benzyl-2-{2-[2-(1-carbamimidoyl-piperidin-4-...)
Affinity DataKi:  370nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113802(5-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]...)
Affinity DataKi:  550nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113799(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  700nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113794(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  720nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113790(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  810nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113791(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  1.10E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113796(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113801(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113786(4-{2-[1-(2-Amino-3-phenyl-propionyl)-piperidin-2-y...)
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113792(S-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethy...)
Affinity DataKi:  1.93E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113798(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  2.90E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113789(4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]...)
Affinity DataKi:  4.80E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113795(RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-eth...)
Affinity DataKi:  5.00E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113788(4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]...)
Affinity DataKi:  5.00E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113784(R-(2-{2-[2-(4-Carbamimidoyl-phenoxy)-ethyl]-piperi...)
Affinity DataKi:  7.30E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113800(RS-(1-Benzyl-2-{2-[2-(1-carbamimidoyl-piperidin-4-...)
Affinity DataKi:  7.90E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113797(S-3-Benzylamino-4-{2-[2-(1-carbamimidoyl-piperidin...)
Affinity DataKi:  9.20E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed