Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50037026
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113810BDBM50113810(4-Naphthalen-1-ylmethyl-5-piperidin-4-yl-isoxazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000687BDBM50000687(4-[6-Amino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113817BDBM50113817(4-(2-Naphthalen-2-yl-ethyl)-5-piperidin-4-yl-isoxa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113815BDBM50113815(4-(2-Naphthalen-1-yl-ethyl)-5-piperidin-4-yl-isoxa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113812BDBM50113812(4-Benzhydryl-5-piperidin-4-yl-isoxazol-3-ol; hydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113824BDBM50113824(4-Phenethyl-5-piperidin-4-yl-isoxazol-3-ol; hydrob...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113806BDBM50113806(CHEMBL544544 | CHEMBL377925 | 4-(3,3-Diphenyl-prop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095533BDBM50095533(CHEMBL144718 | 4-(naphthalen-2-ylmethyl)-5-(piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113804BDBM50113804(4-Anthracen-9-ylmethyl-5-piperidin-4-yl-isoxazol-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113813BDBM50113813(4-Biphenyl-4-ylmethyl-5-piperidin-4-yl-isoxazol-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113805BDBM50113805(4-(3-Phenyl-propyl)-5-piperidin-4-yl-isoxazol-3-ol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113809BDBM50113809(4-Ethyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113803BDBM50113803(4-Methyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113821BDBM50113821(4-Hexyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113822BDBM50113822(5-(4-Methyl-piperidin-4-yl)-isoxazol-3-ol; hydrobr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113819BDBM50113819(4-(4,4-Diphenyl-butyl)-5-piperidin-4-yl-isoxazol-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032954BDBM50032954(5-Piperidin-4-yl-isoxazol-3-ol(4-PIOL) | 5-(piperi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113811BDBM50113811(4-(2,2-Diphenyl-ethyl)-5-piperidin-4-yl-isoxazol-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113818BDBM50113818(5-Piperidin-4-yl-4-propyl-isoxazol-3-ol; hydrobrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113808BDBM50113808(4-Benzyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113814BDBM50113814(4-Cyclohexylmethyl-5-piperidin-4-yl-isoxazol-3-ol;...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113816BDBM50113816(4-Octyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113823BDBM50113823(4-Butyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed