Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50012122 Sort by
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114943((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 0.200nMAssay Description:Tested for inhibitory concentration expressed as displacement of [125I]-labeled substance P from the cloned human Tachykinin receptor 1 expressed in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114944(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114933(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 0.340nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114937(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114939(2-(3,5-Bis-trifluoromethyl-phenyl)-N-{4-[4-(4-fluo...)
Affinity DataIC50: 0.440nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114949(2-(3,5-Bis-trifluoromethyl-phenyl)-N-{4-[4-(4-fluo...)
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114940(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 0.620nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114942(2-(3,5-Bis-trifluoromethyl-phenyl)-N-{4-[4-(4-fluo...)
Affinity DataIC50: 0.630nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114938(2-(3,5-Bis-trifluoromethyl-phenyl)-N-{4-[4-(4-fluo...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114934(2-(3,5-Bis-trifluoromethyl-phenyl)-2-{4-[4-(4-fluo...)
Affinity DataIC50: 0.75nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114937(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 0.770nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114937(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 0.770nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50: 0.950nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114941((3,5-Bis-trifluoromethyl-benzyl)-{4-[4-(4-fluoro-p...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114946(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114935(1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-p...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114936(1-{4-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxymet...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114932(N-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114948(1-{4-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-4...)
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114935(1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-p...)
Affinity DataIC50: 59nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114941((3,5-Bis-trifluoromethyl-benzyl)-{4-[4-(4-fluoro-p...)
Affinity DataIC50: 82nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114938(2-(3,5-Bis-trifluoromethyl-phenyl)-N-{4-[4-(4-fluo...)
Affinity DataIC50: 85nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114947(3,5-Bis-trifluoromethyl-benzoic acid 4-[4-(4-fluor...)
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114945(4-Phenyl-piperidine-4-carboxylic acid 3,5-bis-trif...)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114946(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114933(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50: 150nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114932(N-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl...)
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed