Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50012457
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119033BDBM50119033(3-Furan-2-yl-N-(3-methoxy-4-oxazol-5-yl-phenyl)-ac...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119042BDBM50119042((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-o-tolyl-a...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119017BDBM50119017((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-pyridin-4...)
Affinity DataIC50: 57nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119044BDBM50119044((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-quinolin-...)
Affinity DataIC50: 57nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119013BDBM50119013((E)-3-(2-Chloro-phenyl)-N-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119022BDBM50119022((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-thiophen-...)
Affinity DataIC50: 66nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119009BDBM50119009((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-phenyl-ac...)
Affinity DataIC50: 73nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119027BDBM50119027((E)-3-(4-Fluoro-2,6-dimethyl-phenyl)-N-(3-methoxy-...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119018BDBM50119018(5-Methyl-thiophene-2-carboxylic acid (3-methoxy-4-...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119012BDBM50119012(1H-Indole-2-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119034BDBM50119034((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-(2-methox...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119008BDBM50119008((E)-3-(4-Fluoro-phenyl)-N-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119046BDBM50119046(1-Methyl-1H-indole-2-carboxylic acid (3-methoxy-4-...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119025BDBM50119025(5-tert-Butyl-furan-2-carboxylic acid (3-methoxy-4-...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119020BDBM50119020(Indolizine-2-carboxylic acid (3-methoxy-4-oxazol-5...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119016BDBM50119016(Benzo[b]thiophene-2-carboxylic acid (3-methoxy-4-o...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119043BDBM50119043((E)-3-(3-Fluoro-phenyl)-N-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119031BDBM50119031((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-p-tolyl-a...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119030BDBM50119030(Benzofuran-2-carboxylic acid (3-methoxy-4-oxazol-5...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119029BDBM50119029((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-pyridin-3...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119015BDBM50119015((E)-3-(4-Chloro-phenyl)-N-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119011BDBM50119011(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3,4-dimethyl-be...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119040BDBM50119040((E)-3-(3-Chloro-phenyl)-N-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119010BDBM50119010(Benzo[1,3]dioxole-5-carboxylic acid (3-methoxy-4-o...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119019BDBM50119019((E)-3-(2-Fluoro-phenyl)-N-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119036BDBM50119036(4,5-Dimethyl-furan-2-carboxylic acid (3-methoxy-4-...)
Affinity DataIC50: 540nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119038BDBM50119038((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-a...)
Affinity DataIC50: 590nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119035BDBM50119035(1H-Indole-5-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119032BDBM50119032((E)-3-(1H-Indol-3-yl)-N-(3-methoxy-4-oxazol-5-yl-p...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119028BDBM50119028(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-benzamide | CHE...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119007BDBM50119007(Thiophene-2-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: 810nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119023BDBM50119023(5-Pyridin-2-yl-thiophene-2-carboxylic acid (3-meth...)
Affinity DataIC50: 870nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119014BDBM50119014(1-Methyl-1H-pyrrole-2-carboxylic acid (3-methoxy-4...)
Affinity DataIC50: 890nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119037BDBM50119037((Z)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-(2-methox...)
Affinity DataIC50: 960nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119026BDBM50119026(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-2-phenyl-acetam...)
Affinity DataIC50: 970nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119041BDBM50119041(1H-Indazole-3-carboxylic acid (3-methoxy-4-oxazol-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119012BDBM50119012(1H-Indole-2-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119024BDBM50119024(3-Methyl-furan-2-carboxylic acid (3-methoxy-4-oxaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119039BDBM50119039(Furan-2-carboxylic acid (3-methoxy-4-oxazol-5-yl-p...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119021BDBM50119021(1H-Indole-3-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed