Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50012478
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119349BDBM50119349(2-cyclobutyl-2-{3-phenyl-4-[4-(3-phenylpropyl)hexa...)
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119341BDBM50119341((R)-3-cyclopropyl-2-((3S,4S)-3-phenyl-4-((4-(3-phe...)
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119338BDBM50119338((R)-3-Cyclobutyl-2-{(S)-3-phenyl-4-[4-(3-phenyl-pr...)
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119336BDBM50119336(Cyclohexyl-{3-phenyl-4-[4-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119342BDBM50119342(2-cyclopentyl-2-{3-phenyl-4-[4-(3-phenylpropyl)hex...)
Affinity DataIC50: 0.200nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119321BDBM50119321(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)
Affinity DataIC50: 0.200nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119343BDBM50119343(2-cyclohexyl-2-{3-[4-hydroxy-4-(3-phenylpropyl)hex...)
Affinity DataIC50: 0.5nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119343BDBM50119343(2-cyclohexyl-2-{3-[4-hydroxy-4-(3-phenylpropyl)hex...)
Affinity DataIC50: 0.5nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119333BDBM50119333(3-methyl-2-{3-phenyl-4-[4-(3-phenylpropyl)hexahydr...)
Affinity DataIC50: 0.700nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119337BDBM50119337((R)-2-((3S,4S)-3-((4-hydroxy-4-(3-phenylpropyl)pip...)
Affinity DataIC50: 0.800nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119332BDBM50119332(1-[1-(1-cyclohexyl-2-hydroxyethyl)-4-phenyltetrahy...)
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119331BDBM50119331(1-[1-(1-cyclohexyl-2-hydroxyethyl)-4-phenyltetrahy...)
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119347BDBM50119347((R)-methyl 2-cyclohexyl-2-((3S,4S)-3-((4-hydroxy-4...)
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119345BDBM50119345(2-{3-[4-hydroxy-4-(3-phenylpropyl)hexahydro-1-pyri...)
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119339BDBM50119339((R)-2-((3S,4S)-3-((4-hydroxy-4-(3-phenylpropyl)pip...)
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119335BDBM50119335(2-cyclopropyl-2-{3-phenyl-4-[4-(3-phenylpropyl)hex...)
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119334BDBM50119334(Cyclohexyl-{(S)-3-[4-hydroxy-4-(3-phenyl-propyl)-p...)
Affinity DataIC50: 3.60nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119344BDBM50119344((S)-methyl 2-cyclohexyl-2-((3S,4S)-3-((4-hydroxy-4...)
Affinity DataIC50: 4nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119348BDBM50119348((R)-2-cyclohexyl-2-((3S,4S)-3-((4-(4-fluorophenyl)...)
Affinity DataIC50: 4nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119346BDBM50119346(2-cyclohexyl-2-{3-[4-hydroxy-4-(3-phenylpropyl)hex...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119340BDBM50119340(2-{3-[4-hydroxy-4-(3-phenylpropyl)hexahydro-1-pyri...)
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119329BDBM50119329(Cyclohexyl-{3-[4-hydroxy-4-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 24nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119330BDBM50119330((R)-2-((3S,4S)-3-((4-(4-fluorophenyl)piperidin-1-y...)
Affinity DataIC50: 36nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed