Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50012481
Affinity DataIC50: 0.300nMAssay Description:Evaluated for binding affinity against Melanocortin-4 receptor by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Evaluated for binding affinity against Melanocortin-4 receptor by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Evaluated for binding affinity against rat Melanocortin-4 receptor (rMC4R) by displacing [125I]NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.20nMAssay Description:Evaluated for binding affinity against human Melanocortin-4 receptor (hMC4R) by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Evaluated for binding affinity against Melanocortin-4 receptor by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 326nMAssay Description:Evaluated for binding affinity against human melanocortin 5 (hMC5R) receptor by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 761nMAssay Description:Evaluated for binding affinity against human Melanocortin-3 receptor (hMC3R) by displacing [125I]NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Evaluated for binding affinity against rat Melanocortin-5 receptor (rMC5R) by displacing [125I]NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+3nMAssay Description:Evaluated for binding affinity against rat Melanocortin-3 receptor (rMC3R) by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Evaluated for binding affinity against human melanocortin 1 (hMC1R) receptor by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.05E+3nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 736nMAssay Description:Evaluated for Functional Activity at MC5R as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 737nMAssay Description:Functional activity as concentration at 50% maximum cAMP accumulation in human melanocortin 1 (MC5R) receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 9.60nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 59nMAssay Description:Evaluated for Functional Activity at MC3R as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Evaluated for Functional Activity at MC5R as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 8.70nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 127nMAssay Description:Evaluated for Functional Activity at MC5R as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Functional activity as concentration of the compound at 50% maximum cAMP accumulation in rat Melanocortin-4 receptor (rMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Functional activity as concentration of the compound at 50% maximum cAMP accumulation in human Melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 271nMAssay Description:Evaluated for Functional Activity at MC5R as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.33E+3nMAssay Description:Functional activity as concentration of the compound at 50% maximum cAMP accumulation in rat Melanocortin-3 receptor (rMC3R)More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Functional activity as concentration of the compound at 50% maximum cAMP accumulation in rat Melanocortin-5 receptor (rMC5R)More data for this Ligand-Target Pair
Affinity DataEC50: 2.49E+3nMAssay Description:Evaluated for Functional Activity at MC3R as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.49E+3nMAssay Description:Functional activity as concentration of the compound at 50% maximum cAMP accumulation in human melanocortin 1 (MC3R) receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 771nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.85E+3nMAssay Description:Functional activity as concentration at 50% maximum cAMP accumulation in human melanocortin 1 (MC1R) receptorMore data for this Ligand-Target Pair
