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Found 22 Enz. Inhib. hit(s) with all data for entry = 50012525
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120056(15-Amino-1-methyl-10-thia-tricyclo[7.5.1.0*2,7*]pe...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120057(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120058(7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  4nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120053(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)
Affinity DataKi:  21nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120056(15-Amino-1-methyl-10-thia-tricyclo[7.5.1.0*2,7*]pe...)
Affinity DataKi:  43nMAssay Description:Binding affinity of the compound for Opioid receptor kappa 1 was determined.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  52nMAssay Description:Binding affinity of the compound for Opioid receptor kappa 1 was determined.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120057(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)
Affinity DataKi:  66nMAssay Description:Binding affinity of the compound for Opioid receptor kappa 1 was determined.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  113nMAssay Description:Binding affinity of the compound for Opioid receptor delta 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120061(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)
Affinity DataKi:  135nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120062(7-Amino-6-mercapto-8,8-dimethyl-5,6,7,8-tetrahydro...)
Affinity DataKi:  163nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120058(7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-...)
Affinity DataKi:  184nMAssay Description:Binding affinity of the compound for Opioid receptor kappa 1 was determined.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120054(3-Amino-4,4-dimethyl-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataKi:  204nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120059(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)
Affinity DataKi:  286nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120053(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)
Affinity DataKi:  345nMAssay Description:Binding affinity of the compound for Opioid receptor kappa 1 was determined.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120057(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)
Affinity DataKi:  349nMAssay Description:Binding affinity of the compound for Opioid receptor delta 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120056(15-Amino-1-methyl-10-thia-tricyclo[7.5.1.0*2,7*]pe...)
Affinity DataKi:  420nMAssay Description:Binding affinity of the compound for Opioid receptor delta 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120055(7-Amino-6-methanesulfinyl-8,8-dimethyl-5,6,7,8-tet...)
Affinity DataKi:  1.05E+3nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120055(7-Amino-6-methanesulfinyl-8,8-dimethyl-5,6,7,8-tet...)
Affinity DataKi:  1.06E+3nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120060(7-Amino-6-methanesulfonyl-8,8-dimethyl-5,6,7,8-tet...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity for Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120053(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)
Affinity DataKi:  4.51E+3nMAssay Description:Binding affinity of the compound for Opioid receptor delta 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50120058(7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-...)
Affinity DataKi:  5.22E+3nMAssay Description:Binding affinity of the compound for Opioid receptor delta 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed