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Found 5 Enz. Inhib. hit(s) with all data for entry = 50023927
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250882((23R,25R)-3,4-seco-9beta-H-lanosta-4(28),7-dien-26...)
Affinity DataIC50:  4.26E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250883((2R,4S,6R)-6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-hydroxyp...)
Affinity DataIC50:  5.04E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250884((2R,6R)-methyl 6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-meth...)
Affinity DataIC50:  6.73E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataIC50:  7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Osaka University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250881(CHEMBL518106 | Methyl (23R,25R)-3,4-seco-9beta-H-l...)
Affinity DataIC50:  7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed