Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50035290
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  1nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366779BDBM50366779(METHYLLYCACONITINE)
Affinity DataKi:  4.80nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121739BDBM50121739(CHEMBL216458 | Bungarotoxin,Alpha | Bungarotoxin N...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035415BDBM50035415((S)-1'-demethylnicotine | l-nor-nicotine | US86097...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  340nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035415BDBM50035415((S)-1'-demethylnicotine | l-nor-nicotine | US86097...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366779BDBM50366779(METHYLLYCACONITINE)
Affinity DataKi:  1.46E+3nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121739BDBM50121739(CHEMBL216458 | Bungarotoxin,Alpha | Bungarotoxin N...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121744BDBM50121744(1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-3...)
Affinity DataKi:  3.17E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121745BDBM50121745((R,S)-1-(1-Methyl-piperidin-2-ylmethyl)-4-pyridin-...)
Affinity DataKi:  3.21E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121741BDBM50121741(1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-4...)
Affinity DataKi:  3.89E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121742BDBM50121742((R,S)-1-(1-Methyl-piperidin-2-ylmethyl)-4-pyridin-...)
Affinity DataKi:  4.20E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121749BDBM50121749(1-Pyridin-4-ylmethyl-4-(S)-1-pyrrolidin-2-ylmethyl...)
Affinity DataKi:  4.60E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121736BDBM50121736(CHEMBL6346 | (R,S)Piperidin-2-yl-(4-pyridin-3-ylme...)
Affinity DataKi:  5.48E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121743BDBM50121743((R,S)Piperidin-2-yl-(4-pyridin-4-ylmethyl-piperazi...)
Affinity DataKi:  6.05E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121746BDBM50121746((4-Pyridin-2-ylmethyl-piperazin-1-yl)-(S)-pyrrolid...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121744BDBM50121744(1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-3...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121742BDBM50121742((R,S)-1-(1-Methyl-piperidin-2-ylmethyl)-4-pyridin-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121737BDBM50121737(1-Pyridin-3-ylmethyl-4-(S)-1-pyrrolidin-2-ylmethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121741BDBM50121741(1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-4...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121740BDBM50121740((R,S)-1-Piperidin-2-ylmethyl-4-pyridin-4-ylmethyl-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121740BDBM50121740((R,S)-1-Piperidin-2-ylmethyl-4-pyridin-4-ylmethyl-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121738BDBM50121738((R,S)-1-Piperidin-2-ylmethyl-4-pyridin-3-ylmethyl-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121737BDBM50121737(1-Pyridin-3-ylmethyl-4-(S)-1-pyrrolidin-2-ylmethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121748BDBM50121748((R,S)Piperidin-2-yl-(4-pyridin-2-ylmethyl-piperazi...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121749BDBM50121749(1-Pyridin-4-ylmethyl-4-(S)-1-pyrrolidin-2-ylmethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121748BDBM50121748((R,S)Piperidin-2-yl-(4-pyridin-2-ylmethyl-piperazi...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121746BDBM50121746((4-Pyridin-2-ylmethyl-piperazin-1-yl)-(S)-pyrrolid...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121738BDBM50121738((R,S)-1-Piperidin-2-ylmethyl-4-pyridin-3-ylmethyl-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121743BDBM50121743((R,S)Piperidin-2-yl-(4-pyridin-4-ylmethyl-piperazi...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121745BDBM50121745((R,S)-1-(1-Methyl-piperidin-2-ylmethyl)-4-pyridin-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121736BDBM50121736(CHEMBL6346 | (R,S)Piperidin-2-yl-(4-pyridin-3-ylme...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed