Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50012732
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122077BDBM50122077(N-[1-[5-(6-Amino-hexylamino)-pentylcarbamoyl]-2-(4...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122093BDBM50122093(N-[1-[4-(7-Amino-heptylamino)-butylcarbamoyl]-2-(4...)
Affinity DataKi:  38nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122084BDBM50122084(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  64nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122090BDBM50122090(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  65nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122096BDBM50122096(Hexanoic acid [1-[8-(3-amino-propylamino)-octylcar...)
Affinity DataKi:  68nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122087BDBM50122087(Cyclohexanecarboxylic acid [1-[8-(3-amino-propylam...)
Affinity DataKi:  78nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122085BDBM50122085(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  88nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122086BDBM50122086(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  90nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122095BDBM50122095(N-[8-(3-Amino-propylamino)-octyl]-3-(4-hydroxy-phe...)
Affinity DataKi:  100nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122091BDBM50122091(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  110nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122092BDBM50122092(N-[8-(3-Amino-propylamino)-octyl]-3-(4-hydroxy-phe...)
Affinity DataKi:  110nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122089BDBM50122089(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  130nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122094BDBM50122094(Pyridine-2-carboxylic acid [1-[8-(3-amino-propylam...)
Affinity DataKi:  130nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122093BDBM50122093(N-[1-[4-(7-Amino-heptylamino)-butylcarbamoyl]-2-(4...)
Affinity DataKi:  135nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122086BDBM50122086(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  140nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122078BDBM50122078(N-[1-[7-(4-Amino-butylamino)-heptylcarbamoyl]-2-(4...)
Affinity DataKi:  168nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122094BDBM50122094(Pyridine-2-carboxylic acid [1-[8-(3-amino-propylam...)
Affinity DataKi:  170nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122091BDBM50122091(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  170nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122085BDBM50122085(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  210nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122081BDBM50122081(2-Acetylamino-N-[8-(3-amino-propylamino)-octyl]-3-...)
Affinity DataKi:  220nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122087BDBM50122087(Cyclohexanecarboxylic acid [1-[8-(3-amino-propylam...)
Affinity DataKi:  240nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122083BDBM50122083(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  250nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122089BDBM50122089(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  250nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122092BDBM50122092(N-[8-(3-Amino-propylamino)-octyl]-3-(4-hydroxy-phe...)
Affinity DataKi:  250nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122083BDBM50122083(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  254nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122095BDBM50122095(N-[8-(3-Amino-propylamino)-octyl]-3-(4-hydroxy-phe...)
Affinity DataKi:  280nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122077BDBM50122077(N-[1-[5-(6-Amino-hexylamino)-pentylcarbamoyl]-2-(4...)
Affinity DataKi:  287nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122081BDBM50122081(2-Acetylamino-N-[8-(3-amino-propylamino)-octyl]-3-...)
Affinity DataKi:  300nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122084BDBM50122084(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  330nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122079BDBM50122079(N-[2-[3-(8-Amino-octylamino)-propylamino]-2-hydrox...)
Affinity DataKi:  350nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122082BDBM50122082(N-[1-[9-(2-Amino-ethylamino)-nonylcarbamoyl]-2-(4-...)
Affinity DataKi:  410nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122080BDBM50122080(N-[1-[6-(5-Amino-pentylamino)-hexylcarbamoyl]-2-(4...)
Affinity DataKi:  468nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122096BDBM50122096(Hexanoic acid [1-[8-(3-amino-propylamino)-octylcar...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122078BDBM50122078(N-[1-[7-(4-Amino-butylamino)-heptylcarbamoyl]-2-(4...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122082BDBM50122082(N-[1-[9-(2-Amino-ethylamino)-nonylcarbamoyl]-2-(4-...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122090BDBM50122090(N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122079BDBM50122079(N-[2-[3-(8-Amino-octylamino)-propylamino]-2-hydrox...)
Affinity DataKi:  8.10E+3nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122080BDBM50122080(N-[1-[6-(5-Amino-pentylamino)-hexylcarbamoyl]-2-(4...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122088BDBM50122088(N-[1-{3-[4-(3-Amino-propylamino)-butylamino]-propy...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122088BDBM50122088(N-[1-{3-[4-(3-Amino-propylamino)-butylamino]-propy...)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed