Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50012739
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122190(N-(5-chloro-2-ethylcarbamoylmethoxy-benzyl)-2-(6-m...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122183(N-(5-Chloro-2-ethylcarbamoylmethoxy-benzyl)-2-(6-m...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334(1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARB...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067797(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  5nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(N-(3-Chloro-benzyl)-2-(6-methyl-2-oxo-3-phenylmeth...)
Affinity DataKi:  7nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122186(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122187(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122181(2-(3-Amino-6-methyl-2-oxo-2H-pyrazin-1-yl)-N-(5-ch...)
Affinity DataKi:  12nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122185(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  15nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122180(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  18nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122188(N-(2,5-Dichloro-benzyl)-2-(6-methyl-2-oxo-3-phenyl...)
Affinity DataKi:  24nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122182(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  340nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122189(2-(3-Amino-6-methyl-2-oxo-2H-pyrazin-1-yl)-N-(6-am...)
Affinity DataKi:  900nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122183(N-(5-Chloro-2-ethylcarbamoylmethoxy-benzyl)-2-(6-m...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067797(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122190(N-(5-chloro-2-ethylcarbamoylmethoxy-benzyl)-2-(6-m...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122191(2-(2-{[2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122185(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122181(2-(3-Amino-6-methyl-2-oxo-2H-pyrazin-1-yl)-N-(5-ch...)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122187(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122186(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122180(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(N-(3-Chloro-benzyl)-2-(6-methyl-2-oxo-3-phenylmeth...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122182(2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl-2H-pyr...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122189(2-(3-Amino-6-methyl-2-oxo-2H-pyrazin-1-yl)-N-(6-am...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334(1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARB...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122188(N-(2,5-Dichloro-benzyl)-2-(6-methyl-2-oxo-3-phenyl...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122191(2-(2-{[2-(3-Amino-6-methyl-2-oxo-4-trifluoromethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed